ID A0A813VS93_9BILA Unreviewed; 336 AA.
AC A0A813VS93;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 08-OCT-2025, entry version 13.
DE RecName: Full=Fork-head domain-containing protein {ECO:0000259|PROSITE:PS50039};
GN ORFNames=OXX778_LOCUS8543 {ECO:0000313|EMBL:CAF0842778.1};
OS Brachionus calyciflorus.
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=104777 {ECO:0000313|EMBL:CAF0842778.1, ECO:0000313|Proteomes:UP000663879};
RN [1] {ECO:0000313|EMBL:CAF0842778.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Ploen Becks lab {ECO:0000313|EMBL:CAF0842778.1};
RA Nowell W R.;
RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAF0842778.1}.
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DR EMBL; CAJNOC010001185; CAF0842778.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A813VS93; -.
DR OrthoDB; 10070006at2759; -.
DR Proteomes; UP000663879; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:TreeGrafter.
DR GO; GO:0030154; P:cell differentiation; IEA:TreeGrafter.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR050211; FOX_domain-containing.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829:SF343; FORK-HEAD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000663879}.
FT DOMAIN 119..213
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 119..213
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 84..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..228
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..238
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 336 AA; 38535 MW; DBD28C97A9E9C508 CRC64;
MQQMAQDSNI LDNFEIIDLN LFDGPIQFEQ ILDDVSFFET NSSFNFLNAT NSFHNPVFVN
YNSYESPIQY TFEEYGSLPV SDLDSNQVEE TTSEEESKPD CSSPAEQSKN RRRMANFDKP
PEPYADMIAK AILTSEDNLM QLKDIYTYMT KNYEDFTSKV ETSKWKSAIR HNLSSHSFFI
KTSFKNAQGH FWSIETSYLP LIKEKGTTVG IKKCLNRKPR VQKPRAKKQK IDSTEHQSET
VLAGSTSMVI PQNQELYDAY YTSPIAYNDS AFFSSNENDS SSVSSSSSSS NSSYIYKFLM
NSSPQVETYQ PYGYYTIDNT NNVNYVNLIN QQELSY
//
