ID A0A814C8G4_9BILA Unreviewed; 726 AA.
AC A0A814C8G4;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 08-OCT-2025, entry version 13.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=JXQ802_LOCUS12570 {ECO:0000313|EMBL:CAF0969133.1},
GN PYM288_LOCUS11361 {ECO:0000313|EMBL:CAF0936828.1};
OS Rotaria sordida.
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Bdelloidea; Philodinida; Philodinidae; Rotaria.
OX NCBI_TaxID=392033 {ECO:0000313|EMBL:CAF0936828.1, ECO:0000313|Proteomes:UP000663854};
RN [1] {ECO:0000313|EMBL:CAF0936828.1}
RP NUCLEOTIDE SEQUENCE.
RA Nowell W R.;
RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAF0936828.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAJNOH010000191; CAF0936828.1; -; Genomic_DNA.
DR EMBL; CAJNOL010000260; CAF0969133.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A814C8G4; -.
DR Proteomes; UP000663854; Unassembled WGS sequence.
DR Proteomes; UP000663870; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd16655; RING-Ubox_WDSUB1-like; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR051266; CLCR.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR039510; Vint_dom.
DR InterPro; IPR032838; Vwaint_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF156; VWFA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF04564; U-box; 1.
DR Pfam; PF14623; Vint; 1.
DR Pfam; PF00092; VWA; 1.
DR Pfam; PF14624; Vwaint; 1.
DR SMART; SM00504; Ubox; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000663870}.
FT DOMAIN 118..309
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT COILED 440..467
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 726 AA; 81532 MW; C0C9CDAA4C2C63B1 CRC64;
MSDSSASFLC PISYELIRDP VIDPDDNSYV KNAIEDLIQQ SGISPITRQL LSIHDLCSNQ
ALNIAIDEYH DSIQPDIESN SLPINVHPSE ITISTSYTNE FIHISIQPPQ DESRSSCDIC
CVVDTSGSMS ESAEIQNDKN EQYDLSQLDL VKHALKTIIN SLQSQDRLSI VSFSDNAKIL
FRLTKMDDEG KTNALAAVKK LSNYGSTNLW DVLQTGLEIL SKEQHSIGSI SALFLLTDGC
PNVEPPGGHL KSLKKLKKET NFTCVVNTFG FGYNLNSKLL EDISIFGNCG SYAFIPDGSF
VGTIFVNAIS TLLTTVATNV QLLVHSQHLP PTDYTRWYST NSTSEGTYFH LGSITYGQSK
DLLIPLSRKF TTQCKFTLTY GNTQNIKKSI TFNLTNNLQQ ADLDLITQHK FRLEFVHYVR
TALEKMREIK TKSIFKNRLH KAAINQIQKL EEKLRKYADG KDEFIKDLFT DLTGQVKQAI
EKEDWFNKWG IHFLPSLTCA HLLQFCNNFK DPGVQHYGNG NLFSDIRDEM DDIFCSLPAP
KCSKDGAKIN MSVFYNAAGG CFYGECKVHL INGTTKLIKD IKPGDRIAPH GRMIRFVVKT
ICQNQKANMV ILENDLIITA WHPIRYAGEW IMPCSLVSSV NEISCEAIYN FVLDQGHTML
VNDVECVTLG HGFKEDVVRH SYYGSERVIN DLERLNLEQN NGGLIEITEK MLIRNIKSGL
VDGLQS
//
