ID A0A815HM45_ADIRI Unreviewed; 376 AA.
AC A0A815HM45;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 02-APR-2025, entry version 15.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
DE Flags: Fragment;
GN ORFNames=XAT740_LOCUS31658 {ECO:0000313|EMBL:CAF1354327.1};
OS Adineta ricciae (Rotifer).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Bdelloidea; Adinetida; Adinetidae; Adineta.
OX NCBI_TaxID=249248 {ECO:0000313|EMBL:CAF1354327.1, ECO:0000313|Proteomes:UP000663828};
RN [1] {ECO:0000313|EMBL:CAF1354327.1}
RP NUCLEOTIDE SEQUENCE.
RA Nowell W R.;
RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAF1354327.1}.
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DR EMBL; CAJNOR010002899; CAF1354327.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A815HM45; -.
DR Proteomes; UP000663828; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20342; BRcat_RBR_RNF217; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047551; BRcat_RBR_RNF217.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000663828};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 155..376
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAF1354327.1"
SQ SEQUENCE 376 AA; 42233 MW; BC3C7567DC68CC40 CRC64;
MAEQCLSSST DIPSVINVDS LTHHSLSNKL HVPTITSSSS INTTSSSSSA ASSTSSLTIY
CIETGSVAQS LRRRQSLTNT TTIANNIEIT TTTIDEGRLL NDNDKSCGLL TDVEKTVTLS
DGDDESFDDD DDDDDETIIY DSLDPPSFPT SPNYVSSPCP ICLELAVLQV SPCCYFLCCN
NCWRAHISST INDGRIKIPC VANECNKYLT RESIVNFVRY DPPLHDRYLK LYLNANQNPR
AKTCPRCCHL YSLDATKLVP IVKEKKFRTH NHNKKIPKQV QCSECSLVWC FRCSAPWHEN
MTCKQFIKGD KLLLKWINQK NEEQWNARKC PKCSSLIQRA GGCPHMTCQS CACEFCYLCG
RRYVQIPFIG QHSNKF
//
