ID A0A816YNG4_9BILA Unreviewed; 490 AA.
AC A0A816YNG4;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 18-JUN-2025, entry version 15.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=OVN521_LOCUS11838 {ECO:0000313|EMBL:CAF3943868.1},
GN WKI299_LOCUS32405 {ECO:0000313|EMBL:CAF2163175.1}, XDN619_LOCUS14798
GN {ECO:0000313|EMBL:CAF2081273.1};
OS Rotaria magnacalcarata.
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Bdelloidea; Rotaria.
OX NCBI_TaxID=392030 {ECO:0000313|EMBL:CAF2163175.1, ECO:0000313|Proteomes:UP000663856};
RN [1] {ECO:0000313|EMBL:CAF2163175.1}
RP NUCLEOTIDE SEQUENCE.
RA Nowell W R.;
RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAF2163175.1}.
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DR EMBL; CAJNRG010005925; CAF2081273.1; -; Genomic_DNA.
DR EMBL; CAJNRF010014957; CAF2163175.1; -; Genomic_DNA.
DR EMBL; CAJOBG010001608; CAF3943868.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A816YNG4; -.
DR Proteomes; UP000663856; Unassembled WGS sequence.
DR Proteomes; UP000663866; Unassembled WGS sequence.
DR Proteomes; UP000663887; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20356; Rcat_RBR_HHARI-like; 1.
DR FunFam; 1.20.120.1750:FF:000002; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR048962; ARIH1-like_UBL.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR Pfam; PF21235; UBA_ARI1; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000663866};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 117..330
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT COILED 362..389
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 490 AA; 57191 MW; EC6DDBE69CB1E016 CRC64;
MQSKISLATI TTDEKIKYYL LTENEALHEI TKTVKDVNEI LNLPSTTLVR LILNNFHWDQ
DMLTEKFFTD PEKLFKELNV ANPYLSPSLQ SNPLSPGHAP ERDPMLAVVE QMATDNTNKI
CRTCYSENPS GEFYALRCRH QHCLTCWHSY LEVNIGQHGC LRPIYCLSRC LEVIDDEKIL
ELLSNDQNLC DRYRNNLVKA FVEANRLTQW CPGNGCATIV KLNTYSANRA HVIECDNCKT
TFCFQCSKPW HEPIQCSLLA KWEQKNRDES MTGTWVIANT KDCPKCHSAI EKNGGCNHMT
CRKPGCGYEF CWLCFGDWKS HATQQCNVYH AQATEEAQAT AREILKRYIH YFTRYQAHSQ
SLELESKLKE KVEERQKEME ARAMTYADRQ APDKAFEVLQ QCRRTLKYTY PFAFYLERNN
ESIMFEDNQA HLERTTEILS EFLEREFDGQ HETVLKLKNT TNFCENRRKI LVKDCKDGYS
KQRWIGLDPY
//
