ID A0A817WXC5_9BILA Unreviewed; 753 AA.
AC A0A817WXC5;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 28-JAN-2026, entry version 16.
DE RecName: Full=NAD(P)(+)--arginine ADP-ribosyltransferase {ECO:0000256|RuleBase:RU361228};
DE EC=2.4.2.31 {ECO:0000256|RuleBase:RU361228};
DE AltName: Full=Mono(ADP-ribosyl)transferase {ECO:0000256|RuleBase:RU361228};
GN ORFNames=TIS948_LOCUS24141 {ECO:0000313|EMBL:CAF3360649.1},
GN UJA718_LOCUS13685 {ECO:0000313|EMBL:CAF4318152.1};
OS Rotaria socialis.
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Bdelloidea; Philodinida; Philodinidae; Rotaria.
OX NCBI_TaxID=392032 {ECO:0000313|EMBL:CAF3360649.1, ECO:0000313|Proteomes:UP000663825};
RN [1] {ECO:0000313|EMBL:CAF3360649.1}
RP NUCLEOTIDE SEQUENCE.
RA Nowell W R.;
RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-
CC arginyl-[protein] + nicotinamide + H(+); Xref=Rhea:RHEA:19149,
CC Rhea:RHEA-COMP:10532, Rhea:RHEA-COMP:15087, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17154, ChEBI:CHEBI:29965, ChEBI:CHEBI:57540,
CC ChEBI:CHEBI:142554; EC=2.4.2.31;
CC Evidence={ECO:0000256|ARBA:ARBA00047597,
CC ECO:0000256|RuleBase:RU361228};
CC -!- SIMILARITY: Belongs to the Arg-specific ADP-ribosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009558, ECO:0000256|RuleBase:RU361228}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAF3360649.1}.
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DR EMBL; CAJNXB010004157; CAF3360649.1; -; Genomic_DNA.
DR EMBL; CAJOBP010001871; CAF4318152.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A817WXC5; -.
DR OrthoDB; 5986190at2759; -.
DR Proteomes; UP000663825; Unassembled WGS sequence.
DR Proteomes; UP000663873; Unassembled WGS sequence.
DR GO; GO:0106274; F:NAD+-protein-arginine ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 3.90.176.10; Toxin ADP-ribosyltransferase, Chain A, domain 1; 1.
DR InterPro; IPR000768; ART.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_rpt.
DR PANTHER; PTHR45641:SF19; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF01129; ART; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13424; TPR_12; 3.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF56399; ADP-ribosylation; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 5.
DR PROSITE; PS50293; TPR_REGION; 3.
DR PROSITE; PS51996; TR_MART; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU361228}; NAD {ECO:0000256|RuleBase:RU361228};
KW NADP {ECO:0000256|RuleBase:RU361228};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000663873};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361228}.
FT REPEAT 466..499
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 510..543
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 554..587
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 596..629
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 638..671
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 753 AA; 87193 MW; 7B47F12E383BD03D CRC64;
MAYNALIKSL EPEKVSPVFT NDESSENINE DLALVWFDQY MDEIENQSDV EITKGLLRQI
HHYVIFFTEP DACIDYLKSI SKEKTFLIIS GSYAIEYLDK IHSMQQVDSV FIFCLYLEKY
LGLKEKYSKV IDVFNQQPEL IDSLSKNVEL AVRQASIFGL FDGKERSTRY LTREAGSFLW
FQLLTDVLRN ITKTDKHNTG IEDMLMHCQA YYRGNRLELK NIEEFRKKYR PEDAIVWYSK
QSFVYRLVNK ALRTEDIDAL YTFRVYITHL RTQIAIEHQK LRTAASTSKT KIIRLYRGLK
LTKNELLQMR DNAGCLISMN GFFSTSRDIE QAARFATKKS QRKEVVGVLL EIGGNIVWDK
MIFADIAQYS AFPKEQEVLF DLATVFKIVH VEFDESRKLW MMQLSGVDES SSAVNKYIQS
IGRETEESNS ILLFSRVMCD MGEYEKSEKY LKRLLSDLPS NHDDTSKIYF NLGRVCYLRG
EYKQSLEYFE EALAIQKREI HPHESSLEIA RTLHNIGNIY LDQKKVSTAL EYYEKALEMK
RKILHDQPKH PSIATSLTAI GSVYKKRGNL SQALELLQHA YAMKKLTLAA DHPSLADSLD
NLGTIYEEMN NHEKAIECYK QALKIKKQTL PTAHPSISAT LNNMGIVYRK EGNYDKSLSC
YTQALAIEQT KLSLDNLDLA DTYNNLCTLY CEQSFYQKAL EMAQLKLNIL KKHFDDDDEQ
IRLTKALIDE ISEEISPQSD TKAIDEDSLR TFF
//
