UniProt: A0A818HPJ6

Database: UniProt
Entry: A0A818HPJ6_9BILA

LinkDB:  A0A818HPJ6_9BILA 
Original site:  A0A818HPJ6_9BILA

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Ontology (3)   
   GO (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
DNA sequence (11)   
   EMBL (11)   
Protein domain (7)   
   InterPro (4)   
   Pfam (1)   
   PROSITE (1)   
   SMART (1)   
All databases (22)   

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ID   A0A818HPJ6_9BILA        Unreviewed;       451 AA.
AC   A0A818HPJ6;
DT   29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 1.
DT   02-APR-2025, entry version 13.
DE   RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE            EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN   ORFNames=BAC187_LOCUS26233 {ECO:0000313|EMBL:CAF4908540.1},
GN   CBO169_LOCUS11541 {ECO:0000313|EMBL:CAF3465181.1}, DUG663_LOCUS15000
GN   {ECO:0000313|EMBL:CAF3511334.1}, LEP731_LOCUS15037
GN   {ECO:0000313|EMBL:CAF3508256.1}, NFQ510_LOCUS19360
GN   {ECO:0000313|EMBL:CAF4813262.1}, NZN594_LOCUS25913
GN   {ECO:0000313|EMBL:CAF1212688.1}, NZN594_LOCUS27181
GN   {ECO:0000313|EMBL:CAF1235772.1}, NZO219_LOCUS15134
GN   {ECO:0000313|EMBL:CAF3480220.1}, PXF425_LOCUS11264
GN   {ECO:0000313|EMBL:CAF4739309.1}, XKC960_LOCUS23162
GN   {ECO:0000313|EMBL:CAF1135239.1}, XPS770_LOCUS10463
GN   {ECO:0000313|EMBL:CAF4638245.1};
OS   Rotaria sp. Silwood1.
OC   Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC   Bdelloidea; Rotaria.
OX   NCBI_TaxID=2762511 {ECO:0000313|EMBL:CAF3511334.1, ECO:0000313|Proteomes:UP000663839};
RN   [1] {ECO:0000313|EMBL:CAF3511334.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Nowell W R.;
RL   Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC         EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CAF3511334.1}.
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DR   EMBL; CAJNOF010000195; CAF1135239.1; -; Genomic_DNA.
DR   EMBL; CAJNOP010000058; CAF1212688.1; -; Genomic_DNA.
DR   EMBL; CAJNOP010000066; CAF1235772.1; -; Genomic_DNA.
DR   EMBL; CAJNZF010000039; CAF3465181.1; -; Genomic_DNA.
DR   EMBL; CAJNYZ010000077; CAF3480220.1; -; Genomic_DNA.
DR   EMBL; CAJNZB010000057; CAF3508256.1; -; Genomic_DNA.
DR   EMBL; CAJNZC010000071; CAF3511334.1; -; Genomic_DNA.
DR   EMBL; CAJOBT010001276; CAF4638245.1; -; Genomic_DNA.
DR   EMBL; CAJOBW010002246; CAF4739309.1; -; Genomic_DNA.
DR   EMBL; CAJOBU010003880; CAF4813262.1; -; Genomic_DNA.
DR   EMBL; CAJOBV010004921; CAF4908540.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A818HPJ6; -.
DR   OrthoDB; 1431934at2759; -.
DR   Proteomes; UP000663821; Unassembled WGS sequence.
DR   Proteomes; UP000663822; Unassembled WGS sequence.
DR   Proteomes; UP000663830; Unassembled WGS sequence.
DR   Proteomes; UP000663835; Unassembled WGS sequence.
DR   Proteomes; UP000663839; Unassembled WGS sequence.
DR   Proteomes; UP000663847; Unassembled WGS sequence.
DR   Proteomes; UP000663858; Unassembled WGS sequence.
DR   Proteomes; UP000663871; Unassembled WGS sequence.
DR   Proteomes; UP000663876; Unassembled WGS sequence.
DR   Proteomes; UP000663878; Unassembled WGS sequence.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR   CDD; cd20335; BRcat_RBR; 1.
DR   Gene3D; 3.30.60.90; -; 1.
DR   InterPro; IPR031127; E3_UB_ligase_RBR.
DR   InterPro; IPR002867; IBR_dom.
DR   InterPro; IPR044066; TRIAD_supradom.
DR   InterPro; IPR043145; Znf_ZZ_sf.
DR   PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR   Pfam; PF01485; IBR; 1.
DR   SMART; SM00647; IBR; 1.
DR   SUPFAM; SSF57850; RING/U-box; 3.
DR   PROSITE; PS51873; TRIAD; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000663835};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          102..392
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51873"
FT   COILED          276..303
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   451 AA;  53199 MW;  F32268AD6D6ACDA8 CRC64;
     MAAFQKHVTS CDPDHMAPCE YCRCLYNFRH LDEHSRYCRN ISVYQQRQAF IDFILPRLKY
     PFTPVQVRFY IERQKQYQQM LDSHKIIDAL ATFEDKFPFE VPTLDCGVCM EACPYEDIFV
     FGCKDDHKLC YTCFEQSCTT KMNSNEVLTC GLCNYQLQDG EINQLRVPRD RKRVFHEYQI
     QKTFNNLVNN TRGFIRCPNK DCKWVLEARN PDERFRVVCR CCANEFCSIC NQQYHYRTTC
     QQVTQITQQW SVWCNTERGK YLRARAGQDA AYQAQLDDYE SQKAANTQRN EELRRRYDEL
     KADEDLKAKS CRLCPHCKRI VERVAGCSSM ICGRNYHGGD QQSGCGKNFN WDTAEPYIPS
     MNAAAEKIKN DLPHPKNKHR VVHKGIRCNG CNDEIEGIRF DCIHCSSLNY CEKCEQRCTL
     NHSEELRQQK RQQHVFRLIT IPEVSPKRQR H
//

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