ID   A0A820UHN1_9BILA        Unreviewed;       253 AA.
AC   A0A820UHN1;
DT   29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 1.
DT   08-OCT-2025, entry version 13.
DE   RecName: Full=Thiamin pyrophosphokinase thiamin-binding domain-containing protein {ECO:0000259|SMART:SM00983};
DE   Flags: Fragment;
GN   ORFNames=OVN521_LOCUS39744 {ECO:0000313|EMBL:CAF4482974.1};
OS   Rotaria magnacalcarata.
OC   Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC   Bdelloidea; Philodinida; Philodinidae; Rotaria.
OX   NCBI_TaxID=392030 {ECO:0000313|EMBL:CAF4482974.1, ECO:0000313|Proteomes:UP000663866};
RN   [1] {ECO:0000313|EMBL:CAF4482974.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Nowell W R.;
RL   Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CAF4482974.1}.
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DR   EMBL; CAJOBG010050827; CAF4482974.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A820UHN1; -.
DR   Proteomes; UP000663866; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030975; F:thiamine binding; IEA:InterPro.
DR   GO; GO:0004788; F:thiamine diphosphokinase activity; IEA:InterPro.
DR   GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:InterPro.
DR   GO; GO:0006772; P:thiamine metabolic process; IEA:InterPro.
DR   CDD; cd07995; TPK; 1.
DR   FunFam; 2.60.120.320:FF:000001; Thiamine pyrophosphokinase; 1.
DR   Gene3D; 3.40.50.10240; Thiamin pyrophosphokinase, catalytic domain; 1.
DR   Gene3D; 2.60.120.320; Thiamin pyrophosphokinase, thiamin-binding domain; 1.
DR   InterPro; IPR006282; Thi_PPkinase.
DR   InterPro; IPR007373; Thiamin_PyroPKinase_B1-bd.
DR   InterPro; IPR036371; TPK_B1-bd_sf.
DR   InterPro; IPR007371; TPK_catalytic.
DR   InterPro; IPR036759; TPK_catalytic_sf.
DR   NCBIfam; TIGR01378; thi_PPkinase; 1.
DR   PANTHER; PTHR13622; THIAMIN PYROPHOSPHOKINASE; 1.
DR   PANTHER; PTHR13622:SF8; THIAMIN PYROPHOSPHOKINASE 1; 1.
DR   Pfam; PF04265; TPK_B1_binding; 1.
DR   Pfam; PF04263; TPK_catalytic; 1.
DR   SMART; SM00983; TPK_B1_binding; 1.
DR   SUPFAM; SSF63999; Thiamin pyrophosphokinase, catalytic domain; 1.
DR   SUPFAM; SSF63862; Thiamin pyrophosphokinase, substrate-binding domain; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000663866};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          170..242
FT                   /note="Thiamin pyrophosphokinase thiamin-binding"
FT                   /evidence="ECO:0000259|SMART:SM00983"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAF4482974.1"
SQ   SEQUENCE   253 AA;  29183 MW;  AA38E4709AA17EF3 CRC64;
     SMLRRDYTPY SFFDSNTSSN YGIMILNRSL DSVRNLLRKE LWEKANIRAC ADGGSNILKN
     YSDEIHDNFI PDYISGDFDS INEATYEYYK TIPTIEFIKT LDQNATDFTK CVRVMLEKKS
     TLNDLLVFCS LGGRFDHTIG IIHSLYILNN HYPNLQIYLI AECDITFLLH ANKLNRIHIQ
     SIYNGNTCSL SPMSQSAHVE TEGLRWNLCK TQELNFTKLV SSSNTYETKT TSHVDVQTDN
     DIIWTMTYIC DNK
//