ID A0A835EG44_9POAL Unreviewed; 294 AA.
AC A0A835EG44;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 28-JAN-2026, entry version 16.
DE RecName: Full=Ribosomal RNA-processing protein 8 {ECO:0000256|ARBA:ARBA00020203, ECO:0000256|RuleBase:RU365074};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU365074};
GN ORFNames=HU200_039053 {ECO:0000313|EMBL:KAF8693643.1};
OS Digitaria exilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Anthephorinae; Digitaria.
OX NCBI_TaxID=1010633 {ECO:0000313|EMBL:KAF8693643.1, ECO:0000313|Proteomes:UP000636709};
RN [1] {ECO:0000313|EMBL:KAF8693643.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF8693643.1};
RA Bennetzen J.L., Chen S., Ma X., Wang X., Yssel A.E.J., Chaluvadi S.R.,
RA Johnson M., Gangashetty P., Hamidou F., Sanogo M.D., Zwaenepoel A.,
RA Wallace J., Van De Peer Y., Van Deynze A.;
RT "Genome sequence and genetic diversity analysis of an under-domesticated
RT orphan crop, white fonio (Digitaria exilis).";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable methyltransferase required to silence rDNA.
CC {ECO:0000256|RuleBase:RU365074}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU365074}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RRP8 family.
CC {ECO:0000256|ARBA:ARBA00006301, ECO:0000256|RuleBase:RU365074}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF8693643.1}.
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DR EMBL; JACEFO010001924; KAF8693643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A835EG44; -.
DR Gramene; Dexi1B01G0017750.1; Dexi1B01G0017750.1:cds; Dexi1B01G0017750.
DR OrthoDB; 10258825at2759; -.
DR Proteomes; UP000636709; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR FunFam; 1.10.10.2150:FF:000001; Ribosomal RNA-processing protein 8; 1.
DR FunFam; 3.40.50.150:FF:000068; Ribosomal RNA-processing protein 8; 1.
DR Gene3D; 1.10.10.2150; Ribosomal RNA-processing protein 8, N-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR007823; RRP8.
DR InterPro; IPR042036; RRP8_N.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12787; RIBOSOMAL RNA-PROCESSING PROTEIN 8; 1.
DR PANTHER; PTHR12787:SF0; RIBOSOMAL RNA-PROCESSING PROTEIN 8; 1.
DR Pfam; PF05148; Methyltransf_8; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|RuleBase:RU365074};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365074};
KW Reference proteome {ECO:0000313|Proteomes:UP000636709};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW ECO:0000256|RuleBase:RU365074};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|RuleBase:RU365074};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU365074}.
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..26
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..47
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 294 AA; 32874 MW; 66F0DB2EAAAB352B CRC64;
MEPPQESAAG GRKRRRRGGA RNRRKLSSSS QQAPPFPEAA PPPPSSPPSK RRRKDGTGQA
TATPKRGSTS SLLDKMRARL SGGHFRMLNE KLYTCSGQDA FDYFKNDPTL FDVYHTGYQE
QMSHWPEQPV NVIINWLKSH NTSWTVADFG CGNAAVAKNV KNKVFSIDLV SDDPSVIACD
MAHTPLDQSS VDVAIFCLSL MGTNYPSYLE EANRVLKPGG WLVIAEVRSR LDPNNGGADP
EKFSKAIIQL GFSLVSKDMK NKMFILFYFR KKEKSKVAKS IDWPQLKACI YKRR
//
