ID A0A835FNM3_9POAL Unreviewed; 227 AA.
AC A0A835FNM3;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 28-JAN-2026, entry version 15.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=HU200_007944 {ECO:0000313|EMBL:KAF8766009.1};
OS Digitaria exilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Anthephorinae; Digitaria.
OX NCBI_TaxID=1010633 {ECO:0000313|EMBL:KAF8766009.1, ECO:0000313|Proteomes:UP000636709};
RN [1] {ECO:0000313|EMBL:KAF8766009.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF8766009.1};
RA Bennetzen J.L., Chen S., Ma X., Wang X., Yssel A.E.J., Chaluvadi S.R.,
RA Johnson M., Gangashetty P., Hamidou F., Sanogo M.D., Zwaenepoel A.,
RA Wallace J., Van De Peer Y., Van Deynze A.;
RT "Genome sequence and genetic diversity analysis of an under-domesticated
RT orphan crop, white fonio (Digitaria exilis).";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the SINA (Seven in absentia) family.
CC {ECO:0000256|ARBA:ARBA00009119}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF8766009.1}.
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DR EMBL; JACEFO010000522; KAF8766009.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A835FNM3; -.
DR OrthoDB; 4788989at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000636709; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16571; RING-HC_SIAHs; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR052088; E3_ubiquitin-ligase_SINA.
DR InterPro; IPR049548; Sina-like_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR013010; Znf_SIAH.
DR PANTHER; PTHR10315; E3 UBIQUITIN PROTEIN LIGASE SIAH; 1.
DR PANTHER; PTHR10315:SF96; SIAH-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF21362; Sina_RING; 1.
DR Pfam; PF21361; Sina_ZnF; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS51081; ZF_SIAH; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000636709};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00455}.
FT DOMAIN 108..166
FT /note="SIAH-type"
FT /evidence="ECO:0000259|PROSITE:PS51081"
SQ SEQUENCE 227 AA; 24607 MW; 3B26906710D08FB1 CRC64;
MGSPRLPLST YGVEKRVKIE MVANEAPTCS WRLSGMVTAA YVAAEDTGVL DCSVCFFPFK
PPIYQCMMGH AVCSSCRDKL APSGKCHVCG IEIDDYHRCR AMERLVESIH VTCPNAAYGC
DATPLYYDRD DHHRACPHAP LRCPATGCGF LGLTEALLDH FTGAHGWPPA TKARVGDVSG
ALLRDGFNFV LAGGGGGKYL FLLNATRRED KENAIQLVPQ ILITDAV
//
