ID A0A835XJT3_9CHLO Unreviewed; 1516 AA.
AC A0A835XJT3;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 02-APR-2025, entry version 18.
DE RecName: Full=Antiviral helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HYH03_017069 {ECO:0000313|EMBL:KAG2484118.1};
OS Edaphochlamys debaryana.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadales incertae sedis;
OC Edaphochlamys.
OX NCBI_TaxID=47281 {ECO:0000313|EMBL:KAG2484118.1, ECO:0000313|Proteomes:UP000612055};
RN [1] {ECO:0000313|EMBL:KAG2484118.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCAP 11/70 {ECO:0000313|EMBL:KAG2484118.1};
RA Craig R.J., Hasan A.R., Ness R.W., Keightley P.D.;
RT "Comparative genomics of Chlamydomonas.";
RL bioRxiv 0:0-0(2020).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG2484118.1}.
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DR EMBL; JAEHOE010000157; KAG2484118.1; -; Genomic_DNA.
DR OrthoDB; 64767at2759; -.
DR Proteomes; UP000612055; Unassembled WGS sequence.
DR GO; GO:0055087; C:Ski complex; IEA:TreeGrafter.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IEA:TreeGrafter.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR FunFam; 3.40.50.300:FF:000354; ATP-dependent RNA helicase SKI2; 1.
DR Gene3D; 1.10.3380.30; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C-like.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR050699; RNA-DNA_Helicase.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF24; DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH11; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000612055}.
FT DOMAIN 423..578
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 709..917
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 293..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 620..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1072..1102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1133..1155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 975..1002
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 301..314
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..675
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1073..1088
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1090..1102
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1150
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1516 AA; 154704 MW; F5379BBA1BB65983 CRC64;
MELAALPRME LLYGSGGDAA LVPASGDLLP ALVQAPPLGP LLGGSGDAVL AAVRSAYLEH
DTFADLAGCI GTAAHPLLSL FPRAPAWPDV SLPSALVEPT PPPPRGGEGD VGWQVVDVGP
GAGEGGGEAA AAAPGAGRID GLALQRRLAA RGGGADAGWR GLSVSLPYMP GGGVAVLGPP
GPAAAEASSG LWLAQLEAAL GGGGGGGGAL PAVAAPGLGE GLFGGWAAAD GGATAPAAGA
TTPPAAVLPP LPLTTPGGER VTPLAEALAG PRAGLAGTFA DLWLEPELAA AVGNEDEESA
AETAAAAEAD GGAAPSRRRG GVLAELDAEA AAAAGGGGEG AAAAAADDGQ LAKVLAAGAA
AAGSDAAPRR DQASSKLAPG TTAEHPFAAR HSIRNVEEQF NELRPRLALH YPFELDAFQK
EAVLHLEGGR SVFVAAHTSA GKTVVAEYAF ALATKHCTRA IYTSPIKTIS NQKFRDFSAK
FEVGLLTGDV QVRPTAPCLI MTTEILRSML YKGADVIRDV EVVVFDEVHY VNDADRGVVW
EEVIIMLPPH ITLVLLSATV PNVMDFADWV GRTKRKVIHV TGTMKRPVPL EHSLYYGGEI
YPICSREVFN PDGVRKALTA HKARNAPPSS GGGGGGGGGG RGGGFQQGGR GGGGGPGGRG
GGGGGGGGGG RGGPPSGADR ARQQAASAFR GGGGGGPNSS AGSRGERQQL LELVGVLTKR
AMLPVAVFCF SKKRCDSAAD ALSSLDLSSG AEKAAVHGFV ERCLGRLKEG DRALPQILRL
RDLMRRGIAV HHAGLLPIMK EVVEMLFCQG YIKVLFCTET FAMGVNAPTR TVVFHSVRKH
DGKNFRYLLP GEYTQMAGRA GRRGLDAVGH VLLAVWDDGR EPVGESELRA MLTGKGVKLE
SQFRLTYGMI LNLLRVEDLK VEDMLKRSFA EFHAQRSAPA GAAELAGVEA ALRAAAAAPW
PATALGCGRE EVEAYADACE AIEELSAQLQ DALASNKAFQ QALVPGRVVL YGNPINGLTE
PAVVLGDAPA PPPPPVNLTA PAPPGGAAST AATAAANDRW LYLLVLHRPG SVDSEHEAAG
ERERRAREGA AGGRAGGGGG FGGGGGGGLG GMTALASKKN QDLDDMFGGL SVGKGKGKGG
GGGGGGGFGG GPPPPLPVPH YGEEAGLSYA LVADGSRSIT GVCRARLRLD GLDSLLGCGG
SWGEDGVRRA LLGALRGLAR LADEGAGGGG GGGGGGAGAG GGEGEMALLD PRADFRIADV
AAVQALQARA ALQARRAAMR PHRDPGLVEA FTAVRNERRL MRRRRELRHQ LSDASLQQLP
EFELRVGVLQ RLGYLNPDRS VTLKGRVCCE IQSTQDELVA TEAVFSGLLG ELSPEEAVAL
LSALVFQEKS EVEPRLPPAL AAARGALTQL TAATAAVQKE AGLDIAPDQH VTDVLHCGLM
EVVYEWARGT PFAALTDLTD VMEGSIVRAM VRLDGACREL QDAARVMGNT ALFQLAQAAS
AAIKRDVIFA ASLYVA
//
