ID A0A840QSG5_9BACI Unreviewed; 634 AA.
AC A0A840QSG5;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=HNQ41_002667 {ECO:0000313|EMBL:MBB5174452.1};
OS Texcoconibacillus texcoconensis.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Texcoconibacillus.
OX NCBI_TaxID=1095777 {ECO:0000313|EMBL:MBB5174452.1, ECO:0000313|Proteomes:UP000551878};
RN [1] {ECO:0000313|EMBL:MBB5174452.1, ECO:0000313|Proteomes:UP000551878}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24696 {ECO:0000313|EMBL:MBB5174452.1,
RC ECO:0000313|Proteomes:UP000551878};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBB5174452.1}.
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DR EMBL; JACHHB010000013; MBB5174452.1; -; Genomic_DNA.
DR RefSeq; WP_184664877.1; NZ_JACHHB010000013.1.
DR AlphaFoldDB; A0A840QSG5; -.
DR Proteomes; UP000551878; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:MBB5174452.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000551878}.
FT DOMAIN 2..175
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 634 AA; 72014 MW; DD6061A2BF11498A CRC64;
MKRSYTIGMA GHIDHGKTTL TKTLTDIDTD RLKAEKERNI SIELGYAPFH LSEDTQVSIV
DVPGHEKFIR QMIAGVAGID LVLLVVAADE GVMPQTVEHL DILRLLGINE GMIVVTKKDQ
VDEEMIELVE EDIRASIEGT FFEGTELVFV DSLTKEGIDT LKNMIEQHLT QVEPRDTRGA
FRLPIDQVFT VHGQGTVVRG TVYEGTVHEG DVLEVLPSEK KVRARQLQVH HEKRTVGQAG
QRVAVNLGGI SNDELKRGDV LVSTQHYFTT ETIDIHLDTV HQLAFPLKQR MLTKLHIGTA
EVFGTLVFFD RNESAEDEGI LCQLRLQEPI VTKRGDRFIL RRPTPVETIG GGIVIDPKGE
KYKFGEGTIK MLERKREGTP AERILDTLKI EKSATVQLLV EETGIIEDEV KELVADFIEQ
GVIINIGSTY LLNNVYEEIV EVMEADLLEF HENYPMRQGK NKAELIQDLL HYGNELADLA
IEKAAKDGRV KKDGQYISAL DFVSVYPSAW RKRMEQVENT LKEQGLNVEV WGYILENAGI
PERLHEELRH FLLRKKRAIA LDDKHLVSYE SWLEAIEKLY EKTGDAFNLQ EAKSILNVTR
KYLVPLMEQL DERGLTKRIE NERFWQKDPK SILK
//
