ID A0A841JVZ2_9BACT Unreviewed; 632 AA.
AC A0A841JVZ2;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=HNQ77_001085 {ECO:0000313|EMBL:MBB6143141.1};
OS Silvibacterium bohemicum.
OC Bacteria; Pseudomonadati; Acidobacteriota; Terriglobia; Terriglobales;
OC Acidobacteriaceae; Silvibacterium.
OX NCBI_TaxID=1577686 {ECO:0000313|EMBL:MBB6143141.1, ECO:0000313|Proteomes:UP000538666};
RN [1] {ECO:0000313|EMBL:MBB6143141.1, ECO:0000313|Proteomes:UP000538666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 103733 {ECO:0000313|EMBL:MBB6143141.1,
RC ECO:0000313|Proteomes:UP000538666};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBB6143141.1}.
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DR EMBL; JACHEK010000002; MBB6143141.1; -; Genomic_DNA.
DR RefSeq; WP_050062061.1; NZ_JACHEK010000002.1.
DR AlphaFoldDB; A0A841JVZ2; -.
DR OrthoDB; 9804504at2; -.
DR Proteomes; UP000538666; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:MBB6143141.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000538666}.
FT DOMAIN 5..182
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 632 AA; 69058 MW; A2E7C25EBD8C9B9A CRC64;
MTKPSKSIVI GTAGHIDHGK TMLVRALTGV DTDRLPEEKR RGITIDLGFA FLDATGPDGS
SWRISFVDVP GHSLFIRNML AGAGCIDAVL LVISAEEGVK PQTEEHLAIC TLLGVRRGLT
VVTKADAVSP ARLEQVCSDI RTFLSDTFLE ESRAAILPVS AHTGQGIDEL RRELLSLAMS
ATSHNPDHLP RLPLDRAFVM KGFGTVVTGT LLSGELQVGE SLTLEPGSRS VRVRGMQTHG
RPEERVESGS RVALNLAGIE VSDVSRGQTL VSEGTLTSTS VIDVDAMLLP GSSVVKHRSR
VHFHAFTSDT LATVSLYGYE AAEPGVRRLM RLKLQQPIVL VPGDHFVLRQ PSPAATIGGG
RVLDAHPLPN LRKAKCLAWL ESLKDTSPEE QLLLRVARRG SVGLAMHELM AETGFTPEAL
ERHVERFVSS GHLFRIPGNR LLSKECAETG INDISNRLKK SAKSDGLKRS ELKGQTGLNA
AIFDFLIETL ASRQEIRLQD ERIYPAGQPQ SIDPDLKQRS AIATIYEAAG LAAPSSSEVA
VKLGLNESEM RRLMTRLLRE KILIKMGTDA LYIHHGALET LRGRVRELRG QMLDVSGFKQ
LTGLSRKYAI PLLEYLDRER VTRKDGEKRL VL
//
