ID A0A843S504_9BURK Unreviewed; 633 AA.
AC A0A843S504;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 28-JAN-2026, entry version 18.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:MQA19405.1};
GN ORFNames=GEV01_07750 {ECO:0000313|EMBL:MQA19405.1};
OS Rugamonas rivuli.
OC Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC Burkholderiales; Oxalobacteraceae; Telluria group; Rugamonas.
OX NCBI_TaxID=2743358 {ECO:0000313|EMBL:MQA19405.1, ECO:0000313|Proteomes:UP000444318};
RN [1] {ECO:0000313|EMBL:MQA19405.1, ECO:0000313|Proteomes:UP000444318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FT103W {ECO:0000313|EMBL:MQA19405.1,
RC ECO:0000313|Proteomes:UP000444318};
RA Lu H.;
RT "Two novel species isolated from a subtropical stream in China.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MQA19405.1}.
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DR EMBL; WHUF01000002; MQA19405.1; -; Genomic_DNA.
DR RefSeq; WP_152803162.1; NZ_WHUF01000002.1.
DR AlphaFoldDB; A0A843S504; -.
DR Proteomes; UP000444318; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR048931; WHD_2nd_SelB_bact.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF21214; WHD_2nd_SelB_bact; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:MQA19405.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000444318}.
FT DOMAIN 1..172
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 633 AA; 68041 MW; F8FBA5CC86A0697F CRC64;
MIVGTAGHID HGKTTLTRAL TGVDTDRLKE EKARGISIEL GYAYAPLENG EILGVIDVPG
HEKFIRTMAA GVTGIDAALL VIAADDGIMP QTLEHLAILR LLGVRRGAVA LTKIDRADTQ
RVDQVALEIE ALLASTDFAG ARIFRTNAAT AGDAGVDALL RHLSEMAAVL PAADERRLFR
LGVDRVFTLQ GQGTIVTGTA LAGSVRAGDM LQLAPGGQQA RVRSIHAQNS SADTGRAGQR
LALNLGGVAK EDIERGTWVV APALAACSER IDAELTLMPD CGQTLKPWSP VHVHLGAAHR
TANVVLLDGD LLAPGQTARV QLVLPVPVHA VPGDRFVIRN AQATATVGGG VVLDPFGPSR
KRRSAARLAW LQALSDFING GDIGALLARS PLGLRMSALV RLSQLPAKRI ALPQDTIDIA
LQGGDRLLLA GAEVPALEAL ILNGLAGFHE RAPDDAGPER WRLKRIVAPE MEDRLWSRLI
DTLIGDDRIR QRGRSLHLPG HSAELSDSEK AQAAPLLASL LEGRFDPPWV RDLSREHALP
EAELRRLLLK LSRTGEISQV VPDLFYHPQR LAELAELVMA LPEVQASSFR DAAGLGRKRA
IQILEFFDRV GYTRRVGNTH LIRPNAVWLY SGE
//
