ID A0A849AES2_9MICO Unreviewed; 598 AA.
AC A0A849AES2;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 28-JAN-2026, entry version 20.
DE SubName: Full=Selenocysteine-specific translation elongation factor {ECO:0000313|EMBL:NNG38076.1};
GN Name=selB {ECO:0000313|EMBL:NNG38076.1};
GN ORFNames=HJ588_02145 {ECO:0000313|EMBL:NNG38076.1};
OS Flexivirga aerilata.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micrococcales;
OC Dermacoccaceae; Flexivirga.
OX NCBI_TaxID=1656889 {ECO:0000313|EMBL:NNG38076.1, ECO:0000313|Proteomes:UP000557772};
RN [1] {ECO:0000313|EMBL:NNG38076.1, ECO:0000313|Proteomes:UP000557772}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ID2601S {ECO:0000313|EMBL:NNG38076.1,
RC ECO:0000313|Proteomes:UP000557772};
RA Kim D.H.;
RT "Flexivirga sp. ID2601S isolated from air conditioner.";
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NNG38076.1}.
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DR EMBL; JABENB010000001; NNG38076.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A849AES2; -.
DR Proteomes; UP000557772; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:NNG38076.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000557772}.
FT DOMAIN 1..174
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 598 AA; 63233 MW; 7B2CFCD121458E1D CRC64;
MSVHVIATAG HVDHGKSTLV RALTGIEPDR WAEEKRRGLT IDLGFAWTTT PSGREIAFVD
VPGHERFLGN MLAGLGPAPV VCFVVAADEG WREQSTDHRD AVAALGIRHG VIVVTRADKA
PDAVEDVIAQ ARKQLRDTGL AGAPAVAVSA VTGAGLDELR HTLDEVLATV PAPVQDGRVR
LWVDRAFTIT GAGAVVTGTL AAGQIRAEDA LELSGAEGTQ RVVVRGLQHH GTTEQVAQPV
SRTAVNLRGI QAAAIHRGDA LLTPDAWQLV DTVDVRRVSG EALTEVPAQV TAHIGTAAVP
ARLRPFEDDH ARLTFDRRLP LAVSDRIVLR DSGSGRILGG AQVLDADPPE LRRRGDGARR
ADALSALPPG GDVTAEVARR GAVQIATLRR LGIAGASGDA PEGVRPIGGW WVDEQRFEQW
ASALQTAVRE LHARDPLAAG LSRGAAASLL GLPSLDLLAA VVEAAGLQQR DGEISAPGAE
SALGGAEDAV RQLETRLRAR PFDAPEADDL AQLGLGPREL AAAERAGRLL RLRDGVILLP
NGPALAMRAL AELPALFTTS EARQALQATR RVAVPLLEHL DARGWTRRVD NSHREVVR
//
