ID A0A850T0L6_GRUAM Unreviewed; 715 AA.
AC A0A850T0L6;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 28-JAN-2026, entry version 13.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
DE Flags: Fragment;
GN Name=Znf750 {ECO:0000313|EMBL:NWH15291.1};
GN ORFNames=GRUAME_R05578 {ECO:0000313|EMBL:NWH15291.1};
OS Grus americana (Whooping crane).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Gruiformes; Gruidae; Grus.
OX NCBI_TaxID=9117 {ECO:0000313|EMBL:NWH15291.1, ECO:0000313|Proteomes:UP000640762};
RN [1] {ECO:0000313|EMBL:NWH15291.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B10K-DU-012-65 {ECO:0000313|EMBL:NWH15291.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NWH15291.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NWH15291.1}.
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DR EMBL; WEIX01000024; NWH15291.1; -; Genomic_DNA.
DR RefSeq; XP_054702497.1; XM_054846522.1.
DR AlphaFoldDB; A0A850T0L6; -.
DR GeneID; 129214602; -.
DR OrthoDB; 8933073at2759; -.
DR Proteomes; UP000640762; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000640762};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 6..57
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 79..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..92
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..492
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..583
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..676
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NWH15291.1"
FT NON_TER 715
FT /evidence="ECO:0000313|EMBL:NWH15291.1"
SQ SEQUENCE 715 AA; 79173 MW; FA698BDC797DFC36 CRC64;
MSLLKERKPK KPHYIPRPPG KPFKYKCFQC PFTCNEKSHL FNHMKYGLCK NSITLVSEQD
RVIKCPKTSS LEPKQINQLE STVKPTSSKS VTNGLSNLDS KPQYPFAKED AKENVELQNQ
ATNTGIQGQK PAIQKELSSA STTTESTISM QPLLDSIVRP SAFVPVGEHR DSKGPETSDV
SEIIPLSNKS SPFHTKSAFH APTHPWKAGS PFLPEFPHKV APTKGFGSIS PYMQPMIPEY
SPHFYEHRLA IYTPYLLPGN SECESSALSV YGTQDQRHFL PHPGPLPKPI NPSAYEHYRL
FQQYHSTPPI PYGFCRPTDP SFYRFSHIAG INRDQNSHLM EETTLLYPAS LSPSQQYPLS
SHKKQADYEK EMTLLHAKSH SKDDQNEREN AKMSPLAGSA ATGSPGRPSP TNFTQTSHAC
EGLFDLSNKS SSTSLGKYDQ PEENFTAFRP VRKSTDQPTL LQSAQTQQER GDSPTSINVT
DEESHIQNEN HNNEGSLSNT EDDTGIVPLN LSKKADTNTG PIHEHAYKTT SKTESQNFLD
LQDMPLNLSV KDSCNTASLK TSFHSPSHDN GAATASNTEN ETSGADACNP KNPINSACDK
SSFTAHCNEA QDLRIIDSCD EQKQTAAVAL CQLAAYSPSK VRMDNEGQSP QDSKASCTEA
TLNSSDTQDT QCNQKVKGQK RTNQKESAKS QQGTKRVRPN DCSRVFTLRK RTRVS
//
