ID A0A851MFH8_9DEND Unreviewed; 436 AA.
AC A0A851MFH8;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 18-JUN-2025, entry version 15.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
DE Flags: Fragment;
GN Name=Arih1 {ECO:0000313|EMBL:NXC28996.1};
GN ORFNames=CAMPRO_R05589 {ECO:0000313|EMBL:NXC28996.1};
OS Campylorhamphus procurvoides.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Dendrocolaptidae; Campylorhamphus.
OX NCBI_TaxID=190295 {ECO:0000313|EMBL:NXC28996.1, ECO:0000313|Proteomes:UP000614027};
RN [1] {ECO:0000313|EMBL:NXC28996.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B10K-DU-001-09 {ECO:0000313|EMBL:NXC28996.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXC28996.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXC28996.1}.
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DR EMBL; WBMV01003673; NXC28996.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A851MFH8; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000614027; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20343; BRcat_RBR_HHARI-like; 1.
DR CDD; cd20356; Rcat_RBR_HHARI-like; 1.
DR CDD; cd16626; RING-HC_RBR_HHARI; 1.
DR FunFam; 1.20.120.1750:FF:000002; RBR-type E3 ubiquitin transferase; 1.
DR FunFam; 3.30.40.10:FF:000019; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR048962; ARIH1-like_UBL.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR Pfam; PF21235; UBA_ARI1; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:NXC28996.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000614027};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 61..272
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 65..113
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXC28996.1"
FT NON_TER 436
FT /evidence="ECO:0000313|EMBL:NXC28996.1"
SQ SEQUENCE 436 AA; 51628 MW; 5C76F790026EC5BF CRC64;
FSLQNPATIT RILLSHFNWD KEKLMERYFD GNLEKLFAEC HVINPSKKSR TRQMNTRSSA
QDMSCQICYL NYPNSYFTGL ECGHKFCMQC WSEYLTTKIM EEGMGQTISC PAHGCDILVD
DNTVMRLITD SKVKLKYQHL ITNSFVECNR LLKWCPAPDC HHVVKVQYPD AKPVRCKCGR
QFCFNCGENW HDPVKCKWLK KWIKKCDDDS ETSNWIAANT KECPKCHVTI EKDGGCNHMV
CRNQNCKAEF CWVCLGPWEP HGSAWYNCNR YNEDDAKAAR DAQERSRAAL QRYLFYCNRY
MNHMQSLRFE HKLYAQVKQK MEEMQQHNMS WIEVQFLKKA VDVLCQCRAT LMYTYVFAFY
LKKNNQSIIF ENNQADLENA TEVLSGYLER DISQDSLQDI KQKVQDKYRY CESRRRVLLQ
HVHEGYEKDL WEYIED
//
