ID A0A852PPV1_9PASS Unreviewed; 440 AA.
AC A0A852PPV1;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 18-JUN-2025, entry version 15.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
DE Flags: Fragment;
GN Name=Arih1 {ECO:0000313|EMBL:NXY25725.1};
GN ORFNames=ATRCLA_R11873 {ECO:0000313|EMBL:NXY25725.1};
OS Atrichornis clamosus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Menuridae; Atrichornis.
OX NCBI_TaxID=449594 {ECO:0000313|EMBL:NXY25725.1, ECO:0000313|Proteomes:UP000658642};
RN [1] {ECO:0000313|EMBL:NXY25725.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B10K-DU-029-61 {ECO:0000313|EMBL:NXY25725.1};
RC TISSUE=Blood {ECO:0000313|EMBL:NXY25725.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXY25725.1}.
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DR EMBL; WBMZ01016385; NXY25725.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A852PPV1; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000658642; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20343; BRcat_RBR_HHARI-like; 1.
DR CDD; cd20356; Rcat_RBR_HHARI-like; 1.
DR CDD; cd16626; RING-HC_RBR_HHARI; 1.
DR FunFam; 1.20.120.1750:FF:000002; RBR-type E3 ubiquitin transferase; 1.
DR FunFam; 3.30.40.10:FF:000019; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR048962; ARIH1-like_UBL.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR Pfam; PF21235; UBA_ARI1; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:NXY25725.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000658642};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 65..276
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 69..117
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXY25725.1"
FT NON_TER 440
FT /evidence="ECO:0000313|EMBL:NXY25725.1"
SQ SEQUENCE 440 AA; 52101 MW; 9B82BE3246C5D50A CRC64;
IVFLSFLQNP ATITRILLSH FNWDKEKLME RYFDGNLEKL FAECHVINPS KKSRTRQMNT
RSSAQDMSCQ ICYLNYPNSY FTGLECGHKF CMQCWSEYLT TKIMEEGMGQ TISCPAHGCD
ILVDDNTVMR LITDSKVKLK YQHLITNSFV ECNRLLKWCP APDCHHVVKV QYPDAKPVRC
KCGRQFCFNC GENWHDPVKC KWLKKWIKKC DDDSETSNWI AANTKECPKC HVTIEKDGGC
NHMVCRNQNC KAEFCWVCLG PWEPHGSAWY NCNRYNEDDA KAARDAQERS RAALQRYLFY
CNRYMNHMQS LRFEHKLYAQ VKQKMEEMQQ HNMSWIEVQF LKKAVDVLCQ CRATLMYTYV
FAFYLKKNNQ SIIFENNQAD LENATEVLSG YLERDISQDS LQDIKQKVQD KYRYCESRRR
VLLQHVHEGY EKDLWEYIED
//
