ID A0A875S5I4_EENNA Unreviewed; 840 AA.
AC A0A875S5I4;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 13.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744, ECO:0000256|RuleBase:RU361161};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744, ECO:0000256|RuleBase:RU361161};
GN ORFNames=FOA43_002643 {ECO:0000313|EMBL:QPG75292.1};
OS Eeniella nana (Yeast) (Brettanomyces nanus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Pichiomycetes;
OC Pichiales; Pichiaceae; Brettanomyces.
OX NCBI_TaxID=13502 {ECO:0000313|EMBL:QPG75292.1, ECO:0000313|Proteomes:UP000662931};
RN [1] {ECO:0000313|EMBL:QPG75292.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 1945 {ECO:0000313|EMBL:QPG75292.1};
RA Roach M.J.R.;
RL Submitted (OCT-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448,
CC ECO:0000256|RuleBase:RU361161};
CC -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC {ECO:0000256|RuleBase:RU361161}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
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DR EMBL; CP064814; QPG75292.1; -; Genomic_DNA.
DR RefSeq; XP_038778857.1; XM_038922929.1.
DR AlphaFoldDB; A0A875S5I4; -.
DR GeneID; 62196044; -.
DR KEGG; bnn:FOA43_002643; -.
DR OrthoDB; 47059at2759; -.
DR UniPathway; UPA00696; -.
DR Proteomes; UP000662931; Chromosome 3.
DR GO; GO:0008422; F:beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-UniPathway.
DR FunFam; 3.20.20.300:FF:000006; Beta-glucosidase H; 1.
DR FunFam; 2.60.40.10:FF:000495; Periplasmic beta-glucosidase; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR050288; Cellulose_deg_GH3.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR017853; GH.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR037524; PA14/GLEYA.
DR InterPro; IPR011658; PA14_dom.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF27; BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR Pfam; PF07691; PA14; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SMART; SM00758; PA14; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
DR PROSITE; PS51820; PA14; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361161};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Polysaccharide degradation {ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000662931}.
FT DOMAIN 403..563
FT /note="PA14"
FT /evidence="ECO:0000259|PROSITE:PS51820"
SQ SEQUENCE 840 AA; 92913 MW; AEF21622C2A11421 CRC64;
MTFDVDNLLE QLTTEEKVSL ISAVDFWHTA KIERLGIPSI RVSDGPNGIR GTKFFDGVPS
ACFPNGTCLA STFDAELLEK AGELMAREAD HKGAQVILGP TTNIQRGPLG GRGFESFSED
PYLSGISTAS IVGGIQKTGK VAATVKHFVC NDLEHERFSS NSVVSERALR EIYLEPFRLA
IKLADPKCIM TSYNKVNGVH CSENYKLTQK ILRGEWKWNG MIMSDWYGTY SSVEAIQHGI
DIEFPGPTRF RKWDVIKHLL QSKENDLREG DIDDRCRHVL DLVKYVVDSR GEGPYSTLED
TKNNTPKTSA TLRKIAADGI VLLKNDKNVL PLSKGKSTVV IGPNAVALNT YSGGGSASLN
PYYVVTPLEG IKNKVDNVDF TIGCHSHKAL GGLFESMTND LDKSKKGVRA RFYTKPIDER
SSAEKPIDEL VVRNSYVTLF DYSNAAVDTK TKLFYTDFEG VFTPTETADY EFGCQVFGTA
LIYLNDKLLI DNKTHQTKGT FCFSSGTVEE TAVAHLKAGE NYKIRVEFGS GITSKLASDF
GAGGLQVGVT KVIDAEKEIQ HAVSLAKSHD NVILCIGLNS EWESEGYDRD DMTLPRKTND
LVSAVLKANP NTVVVNQSGT PVEMPWLKDC QTLVQAWYGG NELGNAIADV LFGDVVPSGK
LSLSWPFKNQ DNPAYLNFHT EKGRVLYGED VFVGYRYYEK LQSQVAFPFG YGLSYTTFKY
DDLKVTVNDT TVTASFTVAN SGDKYTGKEA VQLYVASLNP SVIRPVKELK AFAKTELKPG
ESQTIKLSLN LKEACSYFDE YENKWCLEAG KYQIQVGSSS DDIHLIGDFE VQKTVYFLEL
//
