ID A0A8A4TU29_SULCO Unreviewed; 624 AA.
AC A0A8A4TU29;
DT 25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 1.
DT 28-JAN-2026, entry version 17.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:QTD52973.1};
GN ORFNames=J3U87_10955 {ECO:0000313|EMBL:QTD52973.1};
OS Sulfidibacter corallicola.
OC Bacteria; Pseudomonadati; Acidobacteriota; Holophagae;
OC Acanthopleuribacterales; Acanthopleuribacteraceae; Sulfidibacter.
OX NCBI_TaxID=2818388 {ECO:0000313|EMBL:QTD52973.1, ECO:0000313|Proteomes:UP000663929};
RN [1] {ECO:0000313|EMBL:QTD52973.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=M133 {ECO:0000313|EMBL:QTD52973.1};
RA Wang G.;
RT "Acanthopleuribacteraceae sp. M133.";
RL Submitted (MAR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CP071793; QTD52973.1; -; Genomic_DNA.
DR RefSeq; WP_237383072.1; NZ_CP071793.1.
DR AlphaFoldDB; A0A8A4TU29; -.
DR KEGG; scor:J3U87_10955; -.
DR Proteomes; UP000663929; Chromosome.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:QTD52973.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000663929}.
FT DOMAIN 2..175
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 624 AA; 70409 MW; FB6859AA4C73D325 CRC64;
MTASVLIATA GHVDHGKSSL VQTLTGIDPD RWAEEKNRGI TIDLGYAHLN HAGRTYSFVD
VPGHEKFIHN MLSGIGSIDA VLLVIAADES IMPQTEEHAT ALHYLGVTQV HVIISKVDLV
DAEMLSLLHL ELDEWLARFG WEKARRVPFS TRQPETRSSV CELLTELTER RAESRGPARL
SIDRVFAATG SGTVVTGTVE RGSLKRETWV LLEPDDRKAR IRQIQIHGSE THEAGPHTRA
ALNLTGIHYK SIKRGHLVFS DCAPPSSRRI WVRLTRFDPD WAPSPKHHFH LHHLAAHLKG
RLLWCEGDWA ALETREPYPF WALDRGLIRD GSPLQLVAGF EVIHPNPASL KRRKAVAWLS
ALPQPLDLHS WQQAYLESYR DPISLNEITA IGGMPPTLAE GVVLIGEDLV ISAVAARQAL
DRLIAAVTSG HQAAPYKPWL PVPEIKAGLP THTHAEIMWR YTLERAITDE VLEISTNRLR
RKDYRPIWKP RDLELLRRFM TPFDRQGGWL DAREWGPERK GLAAMEQWLT SERCFINLSP
DLLVHFKRLN AIAAHLVASH GREGFSIQDL KTELGLSRKH AIPLLEWLDH AKITRREGDR
RHLVSREIEP LVCDLTLPEP FADL
//
