ID A0A8B8DIT7_CRAVI Unreviewed; 1671 AA.
AC A0A8B8DIT7;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 18-JUN-2025, entry version 19.
DE SubName: Full=LOW QUALITY PROTEIN: ATP-dependent RNA helicase DEAH12, chloroplastic-like {ECO:0000313|RefSeq:XP_022327509.1};
GN Name=LOC111126885 {ECO:0000313|RefSeq:XP_022327509.1};
OS Crassostrea virginica (Eastern oyster).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=6565 {ECO:0000313|Proteomes:UP000694844, ECO:0000313|RefSeq:XP_022327509.1};
RN [1] {ECO:0000313|RefSeq:XP_022327509.1}
RP IDENTIFICATION.
RC TISSUE=Whole sample {ECO:0000313|RefSeq:XP_022327509.1};
RG RefSeq;
RL Submitted (MAR-2025) to UniProtKB.
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DR RefSeq; XP_022327509.1; XM_022471801.1.
DR GeneID; 111126885; -.
DR KEGG; cvn:111126885; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000694844; Chromosome 3.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR CDD; cd20335; BRcat_RBR; 1.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd22585; Rcat_RBR_DEAH12-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C-like.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR056245; KH_DEAH11/12.
DR InterPro; IPR056247; KH_DEAH11/12_2nd.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF81; ATP-DEPENDENT RNA HELICASE DEAH11, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR Pfam; PF24471; KH_DEAH11; 1.
DR Pfam; PF24641; KH_DEAH11_2nd; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000694844};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 227..390
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 420..596
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1456..1671
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT REGION 1..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..39
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..62
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..89
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1671 AA; 190073 MW; 6C9A7A96FE5D7AAD CRC64;
MEREHTDEET NQKDSDGNRQ STEGFPLVDE PENDLDETDT LEKAIVETEE KQSELLERKE
NSSRNIPKSR RGIQRETLEL KKDKSDKNQK QSFQDRPQEG SVSKEEYKID IKTLQHIQTE
AEESLRSHQE KKSDTERKIS ALSSKDDKST QKHKEAEKEA LTAKLEELNQ QQGEFQMCLS
KIINDVELRI GKSIDQEEFN ALMNRFEVES TRLRQALPIY AKRSQIMDTI LQSQVSIILG
ETGSGKSTQI TQYILESSLS SAGKXVCTQP XKVAAVSLAE RVASELNSKV GELVGYQVGM
KSMLSKNTKV LYMTDHMLLN ECLKDPLLKD FSCVVIDEAH ERSVYTDLLL GMIKKCLSQR
RDLRVVVTSA TIDPDVFVKY FGGPELCPVL KVSGRMFPVE IDWLNVSAGT EVVDDYETKA
IETAADIHRT EPPGDILIFL TSQIEIEQCR GKLHALLQMK KDFLILPLHG KLQADEQNLV
FQVTPEGKRK IVLATNVAET SVTIPGIKYV VDTGAVKELS YDSSKKVSSL RVVKVTQSSA
NQRKGRAGRT GPGKCYRLYS QKDYEIMCPT SIPEIQKIHL SHAILKLLQL NVDPLDFDFV
EAPERISMDN AFQHLSGLGA IKKGKITPLG KWIAKLPFEP NLGVFVHDSI DSNVGVEGII
IAASCTVSGS LFYRSGTKEQ KEIADKLKVQ FCHKRGDLFT NLCVFKEWYK VDEKRKGKWC
IDNSINGKAL RIIRDSAKEI MHTLKKDLDI RIEFKFSESV DMERVLQKLL FKSFQNNLCH
FLGHEKAGYH FIDKNQQVIL HPSSALQSLA SFPEWVIVEN ILQTSMDYAL NVTAVADEDI
LDALDNRSLK FDFKDVTERK VTQVVTEYVG IQGHKEFVGP RFCKVRAMQE QLLKQHKDAV
FVIDADRDKG EISIFAPIRD KNIYLQTLKS ALDPIREKIR SETAEHPVIP EIQSVRIVIG
AGGQIQDVLY HDEFKNVFIF GENPGSNDRI KEWFGQYGSI SSFIPKSQKS RNPKYIGQIT
YENSESARKA VNATEKGQCD YTASPPKVKA KSDGGDLLRA RLTWCRRKSR GFGFVEILDE
NKIDMIILSC SSKKVNAGGK YMKIKRKQNE RQDEKKNELY VSGLGESVNE DVLRECFLNN
FDVSEEDIGK VAIVREKKDT RPEMLQSLKS QLEDAFSNNI ERDMFSVSVM EPKPADFTYQ
ASITCKDPEK GLEVCSSMQH NLFIEGHSVS ITPEMNTRLS VLTPVYQRIE KEIERYCEKI
RNETRGRRAT VRRLKNEKYV IDISTDSIES LVDTRNEIQR MLEGEKVNVD RIPDLPHLFT
RDGQEKVRRV MQKTNTTILL DHRNISVSIH GKTEERVLAL EKIKRYVEKL SSSKVRLYDL
KGESKPPGLM KAVILKHGKD LQGLKDLSAL TAIELDLRNH RIKMLGSDDA VAKAVEEIDE
MATQVPGKCS ISITSNEPEC AICLCVIPET EMYRLESCGH PYCKDCVKLN LESTMQRREF
PLKCCHDVCQ MLWAWKDFIY MTNIGFCSLQ NIIDSSISSH VRENKDKVKY CITPDCPMVY
KVTENGGRIV CDKCKTGMCS SCHVEYHDGL LCYQYKLSKG NVNYNNECWI QEWMRQDPIN
RKQCPRCFTG IEKNGGCQHM TCQACTIHIC WTCMETFNSG TECYEHMGTK H
//
