ID A0A8B8G1B7_9HEMI Unreviewed; 326 AA.
AC A0A8B8G1B7;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE SubName: Full=Bardet-Biedl syndrome 5 protein homolog isoform X2 {ECO:0000313|RefSeq:XP_025416401.1};
GN Name=LOC112687729 {ECO:0000313|RefSeq:XP_025416401.1};
OS Sipha flava (yellow sugarcane aphid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aphidomorpha;
OC Aphidoidea; Aphididae; Sipha.
OX NCBI_TaxID=143950 {ECO:0000313|Proteomes:UP000694846, ECO:0000313|RefSeq:XP_025416401.1};
RN [1] {ECO:0000313|RefSeq:XP_025416401.1}
RP IDENTIFICATION.
RC TISSUE=Whole body {ECO:0000313|RefSeq:XP_025416401.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
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DR RefSeq; XP_025416401.1; XM_025560616.1.
DR AlphaFoldDB; A0A8B8G1B7; -.
DR GeneID; 112687729; -.
DR CTD; 129880; -.
DR OrthoDB; 10261999at2759; -.
DR Proteomes; UP000694846; Unplaced.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR030804; BBS5/fem-3.
DR InterPro; IPR014003; BBS5_PH.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR PIRSF; PIRSF010072; DUF1448; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000694846}.
FT DOMAIN 5..59
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 135..189
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
SQ SEQUENCE 326 AA; 37020 MW; D3E792CE2E06A8EB CRC64;
MRNGEKIIDR LEFIEDTKGN SGDKGVLVIT NLRAIWHSMT LARISLSIGY NCIQDISTRI
VNSRLKGITE AIYIQAKYNG LRYEFVFTNL IPGNTRHFTS FIGVFKAYNS SRLYRELKLR
GAIIKNDRLR LLMFETMYSI ANGVWNLSSE QGNLGTFIIT NIRLVWYAES NETFNISLPY
IHINSIKIRE SKFGEVLVIG TNGYSGGFTL GFRIDPKERL RSITKELSSL FHIHSQVPEF
GVHFVITDQV ENNEPVLIPT TLSNNYDEFE DENAIGVSNT LAAYSVSKRG KDGLPQYDFS
LGLAIETLPE GYTMRSLWEV ISITNK
//
