ID A0A8B8L5I5_ABRPR Unreviewed; 886 AA.
AC A0A8B8L5I5;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE SubName: Full=Disease resistance protein RPP13-like {ECO:0000313|RefSeq:XP_027351455.1};
GN Name=LOC113862574 {ECO:0000313|RefSeq:XP_027351455.1};
OS Abrus precatorius (Indian licorice) (Glycine abrus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Abreae; Abrus.
OX NCBI_TaxID=3816 {ECO:0000313|Proteomes:UP000694853, ECO:0000313|RefSeq:XP_027351455.1};
RN [1] {ECO:0000313|Proteomes:UP000694853}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31775284; DOI=10.3390/toxins11120691;
RA Hovde B.T., Daligault H.E., Hanschen E.R., Kunde Y.A., Johnson M.B.,
RA Starkenburg S.R., Johnson S.L.;
RT "Detection of Abrin-Like and Prepropulchellin-Like Toxin Genes and
RT Transcripts Using Whole Genome Sequencing and Full-Length Transcript
RT Sequencing of Abrus precatorius.";
RL Toxins 11:0-0(2019).
RN [2] {ECO:0000313|RefSeq:XP_027351455.1}
RP IDENTIFICATION.
RC TISSUE=Young leaves {ECO:0000313|RefSeq:XP_027351455.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
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DR RefSeq; XP_027351455.1; XM_027495654.1.
DR AlphaFoldDB; A0A8B8L5I5; -.
DR GeneID; 113862574; -.
DR KEGG; aprc:113862574; -.
DR OrthoDB; 3027644at2759; -.
DR Proteomes; UP000694853; Unplaced.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0098542; P:defense response to other organism; IEA:TreeGrafter.
DR CDD; cd14798; RX-CC_like; 1.
DR FunFam; 3.40.50.300:FF:001091; Probable disease resistance protein At1g61300; 1.
DR FunFam; 1.10.10.10:FF:000322; Probable disease resistance protein At1g63360; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR055414; LRR_R13L4/SHOC2-like.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR058922; WHD_DRP.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1193; DISEASE RESISTANCE PROTEIN RPP13-RELATED; 1.
DR Pfam; PF23598; LRR_14; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR Pfam; PF23559; WHD_DRP; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000694853};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 5..90
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 168..350
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 432..508
FT /note="Disease resistance protein winged helix"
FT /evidence="ECO:0000259|Pfam:PF23559"
FT DOMAIN 559..755
FT /note="Disease resistance R13L4/SHOC-2-like LRR"
FT /evidence="ECO:0000259|Pfam:PF23598"
SQ SEQUENCE 886 AA; 102523 MW; 2E6ABFF3388AE4CE CRC64;
MADTVVSSLL QNLSQLLGDE FKLLSGVKDR INSLRNDLRF IDIFLKRSMG NRNDELVKEV
VNQIRDVAFK AEDVVDIYVA RIAEHRSRNT VSKLFHLKER FMVLHEVNDE IEKIKNRIEE
IYKNRERYCI TERASTGEDV DAIAAAESLR ERRKDVEEKD VVGFVNDLNF VIKKLVEEGD
SGRKVASIIG MGGLGKTTFA RKIYNNEQVK NCFPLRAWGY VSNDYRAREL LLSLLKCLLS
ISEYDGLFKK KEDEVEDIAG SEEKLKTKVR ECLKGKKYLV VLDDIWKIEV WNSIEDAFPD
DDDGSVGRIL ITSREMEVAN YVGTVSPYHL PFLNVEESWH LFSKKVFRGN ECPSDLEPLG
RSIVETCKGL PLAIVVLAGH ASKKEKSVRE WTRIKKITWD LTQDKMKVMD ILKLSYDSLP
QRLKPCFLYF GIYPEDYEIR ARDVIQMWIA EGFIQPQEAR IQGAAEPEDV AEYYLDELVD
RSLVQVASRK SDGRVKTCQI HDLLRDLCIS ESKSEKFMEV CRDPNDMDTV SNANPRRLSI
QCKEWSNFST NNLNQLCTRS LFFFSEGEMF REDVRLESFK LARVICSNTE RYYYNSALMI
DFKKMIHLRY LRIDARAISI PASVRNLRNL ETLDVRGAEM VSNEIWKLKR LKHLYIRNVE
KIQVLPKSQR KIKGNLQTLL LRCYKSEDLV SLLNNDIFPR LRNLVLFSED YFRHEPLPSL
NHLPNLHSLK INNSQELPSD ANVFPSNLTK ITLHGFMQPG NVLIFLKNMK TVGQLASLQI
LKLKVDIRTD FNVGAGEFPR LKVFQMSKMR VRSWTLEKGA MPCLQNLVIE NCDKLEEIPE
ELWSLTTLRE VQLSNANKRL ADRLRSVELK NGCKLILSEL SPKKRI
//
