ID A0A8B9DYG9_ANSCY Unreviewed; 518 AA.
AC A0A8B9DYG9;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 18-JUN-2025, entry version 18.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN Name=LOC106049319 {ECO:0000313|Ensembl:ENSACDP00005013611.1};
OS Anser cygnoides (Swan goose).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anserinae; Anser.
OX NCBI_TaxID=8845 {ECO:0000313|Ensembl:ENSACDP00005013611.1, ECO:0000313|Proteomes:UP000694521};
RN [1] {ECO:0000313|Ensembl:ENSACDP00005013611.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2025) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR RefSeq; XP_013057034.1; XM_013201580.3.
DR RefSeq; XP_047911158.1; XM_048055201.2.
DR RefSeq; XP_066851409.1; XM_066995308.1.
DR RefSeq; XP_066851410.1; XM_066995309.1.
DR Ensembl; ENSACDT00005016413.1; ENSACDP00005013611.1; ENSACDG00005010021.1.
DR GeneID; 106049319; -.
DR OrthoDB; 1431934at2759; -.
DR Proteomes; UP000694521; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20338; BRcat_RBR_RNF19; 1.
DR CDD; cd20355; Rcat_RBR_RNF19; 1.
DR FunFam; 3.30.40.10:FF:000137; RanBP-type and C3HC4-type zinc finger-containing protein 1; 1.
DR FunFam; 1.20.120.1750:FF:000017; RBR-type E3 ubiquitin transferase; 1.
DR FunFam; 2.20.25.20:FF:000004; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 2.20.25.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 2.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000694521};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 281..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..271
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 56..103
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 19..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..38
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..507
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 55685 MW; 1FF0DBDAF2D8E37D CRC64;
MERPVWVPQP LHVLGFCGQK PEVGGETSPD PEQESGDPEE MHVALPLGED GELVECPLCL
LPQPPEAFPT LASCAHRSCQ ACLEQYLRVA VSESRVQVAC PHCPATLQPA DVHRLLAEPA
LRDKYEEFLL RRLLVADPGT RWCPAPDCSY AVIAYGCAEC PRLTCGREGC GTEFCYHCRQ
PWHPDGPCAP APLTSSLASP SAQLVYPEES ANAEAEDIKV CPRCSAFIMK INDGSCNRMN
CTVCGCLFCW LCLQEISDVH FLSPSGCTFW GKRPWSRTRK ILWQLGMVLG APMVISLVAG
IAVPVITIGL PIYMGRKVLG QSRRSSLSGC QQCFSVTSSV LLSLFVSPII TAVTVGIGVP
LMLTYVYGVV VLSLCRSRSG CGGGRGQPGD LGVVELENLT KLNELWSVLP SPKGVEDGVP
DTTTSFPSSR HSPHHRTVWK EQDSQSASTV ALAGSMLSEG QDGSYREGIN IEVEVAIETV
PHPAREQSLC SALSGQSLSG DSLGGTSDRY SVTGIPAE
//
