ID   A0A8B9YK24_BOSMU        Unreviewed;      1331 AA.
AC   A0A8B9YK24;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   28-JAN-2026, entry version 20.
DE   SubName: Full=Nucleoporin 160 {ECO:0000313|Ensembl:ENSBGRP00000034597.1};
GN   Name=NUP160 {ECO:0000313|Ensembl:ENSBGRP00000034597.1};
OS   Bos mutus grunniens (Wild yak) (Bos grunniens).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=30521 {ECO:0000313|Ensembl:ENSBGRP00000034597.1, ECO:0000313|Proteomes:UP000694520};
RN   [1] {ECO:0000313|Ensembl:ENSBGRP00000034597.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Zhang S., Liu J.;
RL   Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBGRP00000034597.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2025) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSBGRP00000034597.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   Ensembl; ENSBGRT00000039999.1; ENSBGRP00000034597.1; ENSBGRG00000020390.1.
DR   GeneTree; ENSGT00390000000972; -.
DR   Proteomes; UP000694520; Chromosome 13.
DR   GO; GO:0005643; C:nuclear pore; IEA:TreeGrafter.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IEA:TreeGrafter.
DR   InterPro; IPR059141; Beta-prop_Nup120_160.
DR   InterPro; IPR021717; Nucleoporin_Nup160.
DR   InterPro; IPR056547; NUP160_helical.
DR   InterPro; IPR056536; TPR_NUP160_C.
DR   InterPro; IPR056535; TPR_NUP160_M.
DR   PANTHER; PTHR21286; NUCLEAR PORE COMPLEX PROTEIN NUP160; 1.
DR   PANTHER; PTHR21286:SF0; NUCLEAR PORE COMPLEX PROTEIN NUP160; 1.
DR   Pfam; PF11715; Beta-prop_Nup120_160; 2.
DR   Pfam; PF23345; NUP160_helical; 1.
DR   Pfam; PF23354; TPR_NUP160_120_M; 1.
DR   Pfam; PF23347; TPR_Nup160_C; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694520};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          71..255
FT                   /note="Nucleoporin Nup120/160 beta-propeller"
FT                   /evidence="ECO:0000259|Pfam:PF11715"
FT   DOMAIN          287..469
FT                   /note="Nucleoporin Nup120/160 beta-propeller"
FT                   /evidence="ECO:0000259|Pfam:PF11715"
FT   DOMAIN          491..721
FT                   /note="NUP160 helical"
FT                   /evidence="ECO:0000259|Pfam:PF23345"
FT   DOMAIN          765..1029
FT                   /note="NUP160 middle TPR"
FT                   /evidence="ECO:0000259|Pfam:PF23354"
FT   DOMAIN          1074..1331
FT                   /note="NUP160 C-terminal TPR"
FT                   /evidence="ECO:0000259|Pfam:PF23347"
SQ   SEQUENCE   1331 AA;  149753 MW;  C431E12786350BB2 CRC64;
     RPCWCPVGPP VERSFVEVVG AERERPRHFR EFTVCGIGTA NAAAGAVKYG ESAGGFYYVE
     SGKLFSVTRN RFIHWKTSGD TLELVEESLD INLLNNAVRL KFQNCVLLPG GVHVSETQNH
     VIILILTSQT VHRLLLPHPS RMYRSELAIE SQMQSIFTDI GKVDFRDPCN YQPIPSVPGL
     SPGSATSAAW LSNDGEALFA LPSASGGIFV LKLPPYDIPG VVSVVELKQS SVMQRLLIGW
     MPTAIRGDQG PSDHLRLTAG TGHKLRLAYS PSMGLYLGVY LHAPKRGQET LIDFALTSTD
     IWALWHDAEN QTAVKYINFE HNVAGQWSPV FMQPLPEEEI VIRDDQDPRE MYLQSLFTPG
     RFINAALCKA LQIFCRGTER NLDLSWMELK KEVTLAVESE LQGSVTEYEF SQEEFRSLQQ
     EFWCKFYACC LQYQEALSHP LALHLNPHTS MVCLLKKGYL SFLVPSSLVD HLYLLPDENL
     LTEDETTISD DVDVARDVMC LIKCLRLIGE SVTMDMSVMM EMSCYNLQSP EKAAEQILED
     LITIDVDNVM EDICSKLQEI RNPIHAIGLL IREMDYETEV EMEKGFNPAQ PLNIRMNLSQ
     LYGSSTSGHI VCRSVCKIAS TRFLICRDLL ILQQLLMRLG DAVILGAGQL FQAQQDLLHR
     TAPLLLSYYL IKWGSQCLAT DVPVDTLESN LQHLSVLELT DSGALTANKF VSSPQTIVEL
     FFQEVARKHI ISHLFSQPKA PLSQTGLNWP EMITAVTNYL LQLLWPSNPG CLFLECLMGN
     CQYVQLQDYI QLLHPWCQVN VGSCRFMLGR CYLVTGEGQK ALECFCQAAS EVGKEEFLDR
     LIRSEDGEIV STPRLQYYDK VLRLLDVVGL PELVIQLATS AITEAGDDWK SQATLRTCIF
     KHHLDLGHNS QAYEALTQIP DSSRQLDCLR QLVVVLCERS QLQDLVEFPY VNLHNEVVGI
     IESRARAVDL MTHNYYELLY AFHIYRHNYR KAGTVMFEYG MRLGREVRTI RGLEKQGNCY
     LAAINCLRLI RPEYAWIVQP ASGAVYDRPG ASPKRNHDGE CTAAPTNRQI EILELEDLEK
     ECSLARIRLT LAQHDPSAAA VAGSSSAEEM VTLLVQAGLF DTAISLCQTF KLPLTPVFEG
     LAFKCIKLQF GGEAVQAEAW AWLAANQLSS VITTKESSAT DEAWRLLSAY LERYKVQNNL
     YHHCVINKLL SHGVPLPNWL INSYKKVDAA ELLRLYLNYD LLEEAVELVS EYVDAVLGKG
     HQYFGIEFPL SATAPMVWLP YSSIDQLLQA LGENTANSHN IALSQKILDK LEDYQQKVDK
     ATRDLLYRRN L
//