ID   A0A8C2ZQQ5_CYCLU        Unreviewed;       564 AA.
AC   A0A8C2ZQQ5;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   28-JAN-2026, entry version 20.
DE   RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
OS   Cyclopterus lumpus (Lumpsucker).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Cottales; Cyclopteridae; Cyclopterus.
OX   NCBI_TaxID=8103 {ECO:0000313|Ensembl:ENSCLMP00005030273.1, ECO:0000313|Proteomes:UP000694565};
RN   [1] {ECO:0000313|Ensembl:ENSCLMP00005030273.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2025) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSCLMP00005030273.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A8C2ZQQ5; -.
DR   Ensembl; ENSCLMT00005031623.1; ENSCLMP00005030273.1; ENSCLMG00005014721.1.
DR   GeneTree; ENSGT00530000063870; -.
DR   Proteomes; UP000694565; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR   GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR   InterPro; IPR039363; ZNF750.
DR   InterPro; IPR039064; ZNF750_Znf.
DR   PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR   PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR   Pfam; PF15269; zf-C2H2_7; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694565};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          5..58
FT                   /note="Zinc finger protein 750-like zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF15269"
FT   REGION          60..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          308..345
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          387..473
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          498..564
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..86
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        108..120
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        313..331
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        410..435
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        445..455
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        498..517
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        518..531
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        544..564
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   564 AA;  62629 MW;  4D5772B4AA7F71DF CRC64;
     METAQERKPK RPHYIPRPPG KPYKYHCFQC PFTCNEKSHL FNHMKYNLCK NSISLMSQKN
     GQTARQDCPS PLPAVQNNSP EKQGTKGNKA ESGGDTEEVD VGCDSPVNKE SQSVTKSNTV
     IEGGNENKSL PRPSAFSPVT PKSDGAEAFM PSVQQPEDSQ APVPTFSHPG FPWGTMSSSI
     ALKPFPPPIV PEYTPYLLPD RPLYPPYYLP ANHHANEPNA PSFRPEVMDP PVVPQPIAPP
     HASLFPPYPY RYCHPLHSNP PVHFTLYRPH ELSMPIAGPR YLPLDLYGPA LGPKDYDLYV
     HSRSSLDSLN TSTRKESNHG QRGDKETRLS PKEGCSALGS PDRPSHAHII QRHTEAPHYT
     NKMCCFCNYC PLTGYFHLSD RPRATDISLS DQDSENNRED LTPLNLSTRN QDKEKSPSDH
     RLRCSETENL NREELPLNLS LRPSYSSPVH SSALGTSEDL EPKPETELDE EPCDQRQTAA
     LALCQLAIAR SAASSCGFNT ADRTSENYTD TVSSGSPKKT KHTTVAKKTG VKRANSGQAD
     NKCHKPNKRA KAPGRALRRR PRCC
//