ID   A0A8C3SG29_CHESE        Unreviewed;       876 AA.
AC   A0A8C3SG29;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   28-JAN-2026, entry version 19.
DE   RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE            EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
OS   Chelydra serpentina (Snapping turtle) (Testudo serpentina).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Americhelydia; Chelydroidea; Chelydridae; Chelydra.
OX   NCBI_TaxID=8475 {ECO:0000313|Ensembl:ENSCSRP00000014377.1, ECO:0000313|Proteomes:UP000694403};
RN   [1] {ECO:0000313|Ensembl:ENSCSRP00000014377.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2025) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSCSRP00000014377.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2025) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the ZNF598/HEL2 family.
CC       {ECO:0000256|ARBA:ARBA00035113}.
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DR   AlphaFoldDB; A0A8C3SG29; -.
DR   Ensembl; ENSCSRT00000014990.1; ENSCSRP00000014377.1; ENSCSRG00000011021.1.
DR   OrthoDB; 3838338at2759; -.
DR   Proteomes; UP000694403; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043022; F:ribosome binding; IEA:TreeGrafter.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:TreeGrafter.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:InterPro.
DR   CDD; cd16615; RING-HC_ZNF598; 1.
DR   InterPro; IPR057634; PAH_ZNF598/HEL2.
DR   InterPro; IPR041888; RING-HC_ZNF598/HEL2.
DR   InterPro; IPR044288; ZNF598/HEL2.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   InterPro; IPR059042; Znf_C2H2_ZNF598.
DR   InterPro; IPR001841; Znf_RING.
DR   PANTHER; PTHR22938:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZNF598; 1.
DR   PANTHER; PTHR22938; ZINC FINGER PROTEIN 598; 1.
DR   Pfam; PF23202; PAH_ZNF598; 1.
DR   Pfam; PF25447; RING_ZNF598; 1.
DR   Pfam; PF23208; zf_C2H2_ZNF598; 1.
DR   SMART; SM00355; ZnF_C2H2; 5.
DR   PROSITE; PS50089; ZF_RING_2; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694403};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ   SEQUENCE   876 AA;  97571 MW;  4D1DEDD0E4FD2D6D CRC64;
     MAASPSPAAG PPDGLCVLCC GELEVVALGR CDHPICYRCS VRMRALCGVR YCAVCREELG
     QVVFGRKLAS FSTIPINQLQ HEKKYDICFA DGKVFALYRK LLQHECPLCP DVRPFNTVVD
     LEQHMRKQHE LFCCKLCVKH LKIFTHERKW YSRKDLARHR IHGDPDDTSH RGHPLCKFCD
     ERYLDNDELL KHLRRDHYFC HFCDSDGAQE YYSDYEYLRE HFREKHFLCE EGQCSTEQFT
     HAFRTEIDYK AHKTACHSKN RAEARQNRQI DLQFNYASRH QRRNEGVVGG EDFEEVDRYN
     RQGRAGRSGL RGGQQNRRGS WRYKREEEDR DIAAAVRASV AAKRQEEKKQ VEDKEDGSRG
     KKEELRDPEV SSTKRVPKPS NEATVPKEAA ANGALSQDDF PAIGSAAGPL QRSAQPASVK
     LKEEDFPSLS SSAAPTIASG VSLTYTVAAK KTAFQEEDFP ALVSKMRPNA RTVSNITSAW
     SNSSNKSAVK AITSLSSSSN RLAKKPAPSN SNKGSRKSSK LSLSDDEDSG SGLTTQEIRN
     TPTMFDVSSL LAASTSQTFT KVSKKKKMGV EKQRASSPQL PEETLPPASA LEKLAEAEQT
     PSAPANLHLS DRSADVMNGH LEKSVAICNA SKEPPGLKKP PVTSQCPLSQ EDFPALGSSG
     PSRIPPPGFI SVALLKSPPP PPGLSVPASK PPPGFTVIPS TNVSDPVTTS LNEPKPCRGS
     YLIPEHFQQR NIQLIQSIKE FLQSDESRFN QFKTHSGQFR QGLISAAEYY QSCRELLGEN
     FTKIFNELLL LLPDAAKQQE LLSAHNDFRI KEKQGANKPQ KNKKNVWQMD SASDLDCCIC
     PTCQQVLTPQ DIASHKALHI EDEEFPSLQA ISRIIS
//