ID   A0A8C4WQM1_EPTBU        Unreviewed;       443 AA.
AC   A0A8C4WQM1;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   10-JUN-2026, entry version 20.
DE   SubName: Full=Synapsin IIa {ECO:0000313|Ensembl:ENSEBUP00000008825.1};
OS   Eptatretus burgeri (Inshore hagfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata; Myxini;
OC   Myxiniformes; Myxinidae; Eptatretinae; Eptatretus.
OX   NCBI_TaxID=7764 {ECO:0000313|Ensembl:ENSEBUP00000008825.1, ECO:0000313|Proteomes:UP000694388};
RN   [1] {ECO:0000313|Ensembl:ENSEBUP00000008825.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2026) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Synapse {ECO:0000256|ARBA:ARBA00034103}.
CC   -!- SIMILARITY: Belongs to the synapsin family.
CC       {ECO:0000256|ARBA:ARBA00008243}.
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DR   AlphaFoldDB; A0A8C4WQM1; -.
DR   Ensembl; ENSEBUT00000009337.1; ENSEBUP00000008825.1; ENSEBUG00000005686.1.
DR   GeneTree; ENSGT00940000156062; -.
DR   OMA; VWVDSCA; -.
DR   Proteomes; UP000694388; Unplaced.
DR   GO; GO:0030672; C:synaptic vesicle membrane; IEA:TreeGrafter.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:InterPro.
DR   FunFam; 3.30.1490.20:FF:000008; Synapsin I; 1.
DR   FunFam; 3.30.470.20:FF:000042; Synapsin III; 1.
DR   Gene3D; 3.40.50.20; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR016185; PreATP-grasp_dom_sf.
DR   InterPro; IPR001359; Synapsin.
DR   InterPro; IPR020898; Synapsin_ATP-bd_dom.
DR   InterPro; IPR019736; Synapsin_P_site.
DR   InterPro; IPR020897; Synapsin_pre-ATP-grasp_dom.
DR   PANTHER; PTHR10841; SYNAPSIN; 1.
DR   PANTHER; PTHR10841:SF17; SYNAPSIN; 1.
DR   Pfam; PF02078; Synapsin; 1.
DR   Pfam; PF02750; Synapsin_C; 1.
DR   Pfam; PF10581; Synapsin_N; 1.
DR   PRINTS; PR01368; SYNAPSIN.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR   PROSITE; PS00415; SYNAPSIN_1; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694388};
KW   Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT   DOMAIN          119..212
FT                   /note="Synapsin pre-ATP-grasp"
FT                   /evidence="ECO:0000259|Pfam:PF02078"
FT   DOMAIN          214..416
FT                   /note="Synapsin ATP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02750"
FT   REGION          20..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..90
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   443 AA;  48495 MW;  C04F7C2E9A7386B8 CRC64;
     MMNFLRRRLS DSNFMANLPN GYMMDLQRPD NSQQPPPSTS SQAQSGGSRG GSGGSSPTPI
     QGMGPQTSPS TEQRRPQPTA QTPTGSGFLS SLSNAVRQTT AAAAGLVEHT AGTVSGSSSR
     KFKTVLVIDD QQTDWFDAFC CAGVQVEFSE INLAAYVEGD CTVDVQAFRS GTKISKTFKP
     DFVLIRQHPY SMAGGEDYRS LLIGLQYGGI PSVNSLPAAY SFCCKPWVFS HLIQISKRLG
     PDKFPLIEQT FYPNHREMLT TANFPVVVKI GHAHSGLGKV KVENHYDFQD VAGIVALAQT
     YATAEPYIVG KYDIRVQKIG SNYKAYMRTS ISGSWKANSG SSMLEQIAMT DKYRLWIDAC
     SELFGGLDIC ALKAVHGKDG RDYIIEVIDS CFPLIGEHQE EDRQLVSELV VSRMNQLIPR
     TPIPSPQKPN VSVLSCRARK SFC
//