ID   A0A8C5E838_GOUWI        Unreviewed;       544 AA.
AC   A0A8C5E838;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   28-JAN-2026, entry version 20.
DE   RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN   Name=znf750 {ECO:0000313|Ensembl:ENSGWIP00000017711.1};
OS   Gouania willdenowi (Blunt-snouted clingfish) (Lepadogaster willdenowi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Blenniimorphae; Blenniiformes; Gobiesocoidei; Gobiesocidae;
OC   Gobiesocinae; Gouania.
OX   NCBI_TaxID=441366 {ECO:0000313|Ensembl:ENSGWIP00000017711.1, ECO:0000313|Proteomes:UP000694680};
RN   [1] {ECO:0000313|Ensembl:ENSGWIP00000017711.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Wellcome Sanger Institute Data Sharing;
RL   Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGWIP00000017711.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2025) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSGWIP00000017711.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A8C5E838; -.
DR   Ensembl; ENSGWIT00000019541.1; ENSGWIP00000017711.1; ENSGWIG00000009859.1.
DR   Proteomes; UP000694680; Chromosome 8.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR   GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR   InterPro; IPR039363; ZNF750.
DR   InterPro; IPR039064; ZNF750_Znf.
DR   PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR   PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR   Pfam; PF15269; zf-C2H2_7; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694680};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          5..57
FT                   /note="Zinc finger protein 750-like zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF15269"
FT   REGION          274..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          489..544
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        284..302
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        489..502
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        524..544
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   544 AA;  61469 MW;  F7C53A652875464A CRC64;
     METVQERKPK RPHYIPRPPG KPFKYQCFQC PFTCNEKSHL FNHMKYNLCK NSISLMSKKN
     SQSARQIKAT TKAALVKSKE TANMISSVQK TKSIEEKDLP RPSAFSPVTP NRDGAEVFKE
     AVPQVEDSQP AAPTFTHPGF PWGSIPPSIP VKPLTSLMVP DYPPYLLPDR PLYSPYYLPA
     SHHVSEHNTT SFQSEFLNPQ RPMALQPIVP PHSTQFQPYA YTYCHPLHPG PPMPYAMYRP
     HELSMPITGH RYIPLDLYSA NLSPKDYELY PRTHPTPNTP PVSSKEEIHQ VRSEDKETRF
     SPKEGCSASG SPDRPIQAHI MQKDSEECQN HSTAEKWDCG SRVQKILLLF IKLFCYICKD
     MSNFYSFKMS LSDGDHKDNT DDLTPLNLST KHQNQKRIQS DHRLTCTDSR TIKMPELPLN
     LCLRSSPGSP VHISSLNNPE NPQLQTNNAL EEEPCDQRQT AALALCQLAS ASSAAMPCDF
     TVQPSTDLIE TPSPASAENV TKPTRVKTAG VKRARSVHGE SKNHKPNKRV KAHRRALRRK
     PRCY
//