ID   A0A8C5MBY2_9ANUR        Unreviewed;       572 AA.
AC   A0A8C5MBY2;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   28-JAN-2026, entry version 20.
DE   SubName: Full=Collagen type XV alpha 1 chain {ECO:0000313|Ensembl:ENSLLEP00000012333.1};
GN   Name=COL15A1 {ECO:0000313|Ensembl:ENSLLEP00000012333.1};
OS   Leptobrachium leishanense (Leishan spiny toad).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pelobatoidea; Megophryidae; Leptobrachium.
OX   NCBI_TaxID=445787 {ECO:0000313|Ensembl:ENSLLEP00000012333.1, ECO:0000313|Proteomes:UP000694569};
RN   [1] {ECO:0000313|Ensembl:ENSLLEP00000012333.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2025) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSLLEP00000012333.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2025) to UniProtKB.
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DR   AlphaFoldDB; A0A8C5MBY2; -.
DR   Ensembl; ENSLLET00000012820.1; ENSLLEP00000012333.1; ENSLLEG00000007830.1.
DR   GeneTree; ENSGT00940000158302; -.
DR   OrthoDB; 10060752at2759; -.
DR   Proteomes; UP000694569; Unplaced.
DR   GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR   GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR   GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR   GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR   CDD; cd00247; Endostatin-like; 1.
DR   FunFam; 3.10.100.10:FF:000008; collagen alpha-1(XVIII) chain isoform X1; 1.
DR   FunFam; 3.40.1620.70:FF:000003; Collagen type XVIII alpha 1; 1.
DR   Gene3D; 3.40.1620.70; -; 1.
DR   Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR050149; Collagen_superfamily.
DR   InterPro; IPR010515; Collagenase_NC10/endostatin.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR   PANTHER; PTHR24023:SF1112; COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR   Pfam; PF01391; Collagen; 1.
DR   Pfam; PF20010; Collagen_trimer; 1.
DR   Pfam; PF06482; Endostatin; 1.
DR   SUPFAM; SSF56436; C-type lectin-like; 2.
PE   4: Predicted;
KW   Collagen {ECO:0000256|ARBA:ARBA00023119};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694569}.
FT   DOMAIN          323..366
FT                   /note="Collagen type XV/XVIII trimerization"
FT                   /evidence="ECO:0000259|Pfam:PF20010"
FT   DOMAIN          402..567
FT                   /note="Collagenase NC10/endostatin"
FT                   /evidence="ECO:0000259|Pfam:PF06482"
FT   REGION          25..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          105..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          178..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..115
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        279..292
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        300..310
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   572 AA;  59726 MW;  4479B33ACB2CB6D1 CRC64;
     MITLNDLLLN DTEGLLNNTD FQLQPGPPGL DGRPGVPGFP GPRGHKGDNG NVGSGGVKGE
     KGEPGAIIAE DGSLIAQLLG QKGEPGMMGP PGPMGPPGQP GMKGEFGFPG RPGRPGLNGV
     KGPKGETGSS SLGPRGLPGP PGPPGQIVYI KGTVYPVPPR PHCKMPADAT NGVQNICGHK
     GEKGSFGLPG TKGHKGDTGP PGPPGYPVPN QFLNHYLPSI KGERGEKGDS NNGLFIQGPP
     GSPGRHGERG PKGDSVIGPR GQPGVPGLPG PPGYEIIGPP GPPGPPGPPG PPAIYGSAPA
     PGPPGPPGQP GIPGSKNLAT ATRNIDDMLQ KTHLTLEGTL MYLSESSELY VRVRGGWRKV
     QLGEFISLPA DSPPPPAISG HGYQPLPALS PGINMNYGTP NLHLVALNSP FTGDVRADLQ
     CFQQARAVGL TSTYRAFVSS HLQDLHSVVR KADRFNLPIV NLKGQILFDN WESIFSGNGG
     QFNAQIPIYT FDGINVMTDS TWPQKIIWHG SSLTGIRLVH NYCEAWRTSE MAVSGQASSL
     RSGKLLDQKS YSCSNKFIVL CIENSYMTDT RK
//