ID   A0A8C6P5A2_NOTFU        Unreviewed;       614 AA.
AC   A0A8C6P5A2;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   28-JAN-2026, entry version 19.
DE   RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN   Name=znf750 {ECO:0000313|Ensembl:ENSNFUP00015038645.1};
OS   Nothobranchius furzeri (Turquoise killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Nothobranchiidae;
OC   Nothobranchius.
OX   NCBI_TaxID=105023 {ECO:0000313|Ensembl:ENSNFUP00015038645.1, ECO:0000313|Proteomes:UP000694548};
RN   [1] {ECO:0000313|Ensembl:ENSNFUP00015038645.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GRZ {ECO:0000313|Ensembl:ENSNFUP00015038645.1};
RA   Senf B., Petzold A., Downie B.R., Koch P., Platzer M.;
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNFUP00015038645.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2025) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSNFUP00015038645.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A8C6P5A2; -.
DR   Ensembl; ENSNFUT00015040347.1; ENSNFUP00015038645.1; ENSNFUG00015018642.1.
DR   GeneTree; ENSGT00530000063870; -.
DR   Proteomes; UP000694548; Chromosome sgr05.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR   GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR   InterPro; IPR039363; ZNF750.
DR   InterPro; IPR039064; ZNF750_Znf.
DR   PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR   PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR   Pfam; PF15269; zf-C2H2_7; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694548};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          5..58
FT                   /note="Zinc finger protein 750-like zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF15269"
FT   REGION          89..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          318..501
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          528..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..120
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        170..193
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        329..348
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        367..381
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        390..402
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        442..463
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   614 AA;  68730 MW;  1A430C491072B069 CRC64;
     MDNAQERKPK RPHYIPRPPG KPFKYQCFQC PFTCNEKSHL FNHMKYNLCK NSISLMSQKN
     GQAARQIKAV AKGVSVKSKD CATVLSAVQN KSPESREEEE NKDKSRDDTE VEVGCERSVD
     SDSPSLEKPN ICPEKEISEN NEITDLPRPR LSAFSPVTPN REGAEALKSP EQQADDSQSP
     TINDLSNPWG RISSTNPLKS FTPLVVPEYP PYLWPDRHLY PPYYLPGHVR VNEQSSSFQT
     EFVDSQRPMV RQPITPPHAS PFPPYPYRYC HTLHPAPPMH YSFYRPHELP MQITGHRYVP
     LEVYGQSLGH KDYDLYMYSR PGHNNPHSST EEEAHHGRSS EKATRLSPKE GCSASGSPDR
     PSQADIIQRD EKTSPHTRVD DSQTSTQPRD TSRTTEPIKQ DLTESSQYPS VAACEPGLKS
     GSEENPEDDT EDLAPLNLST RNQDHEEKPE HRLLGSDTER SDVSEFPLNL SLRASPSSLV
     HGSIAVEGPP QGPDEDLDEE RCDQRQTAAL ALCQLATASS VVSSNSFSVM SQSSEGPLGT
     TRNAPLERTQ PPTRQPGNRG NDMPTARLQG SLSRRKKRES RSFNKLVVTG TANCITLALK
     PELKRGLKEK NWHV
//