ID A0A8C6RZB2_NANGA Unreviewed; 358 AA.
AC A0A8C6RZB2;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 {ECO:0008006|Google:ProtNLM};
OS Nannospalax galili (Northern Israeli blind subterranean mole rat) (Spalax
OS galili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Spalacidae; Spalacinae; Nannospalax.
OX NCBI_TaxID=1026970 {ECO:0000313|Ensembl:ENSNGAP00000024837.1, ECO:0000313|Proteomes:UP000694381};
RN [1] {ECO:0000313|Ensembl:ENSNGAP00000024837.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSNGAP00000024837.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
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DR AlphaFoldDB; A0A8C6RZB2; -.
DR Ensembl; ENSNGAT00000030549.1; ENSNGAP00000024837.1; ENSNGAG00000022969.1.
DR GeneTree; ENSGT00390000013839; -.
DR OMA; KINTIVC; -.
DR Proteomes; UP000694381; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR FunFam; 1.10.2020.20:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000694381}.
FT DOMAIN 1..87
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 221..330
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..11
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..198
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 358 AA; 36950 MW; BEB954BE7FFCC317 CRC64;
QHPHSSSQPS VTPGPEDMML PSGLHRGPGF DFPHHCEFKW VPRCPSGRVY MLNFKAGSKR
LFFWMQKPKT GQDEEHCREV SDCLNNLLKS GALGASGSGR HELSALGGEG GFHSQLMQLI
VPAGLGGLGG LGALTGPGLA SLLGSTGPPA SSSSSSSRTV TPSSTTSSAR ATPAPSAPAA
ASATSPSPAP SSGNGTSTAA SPTQPIQLSD LQNILATMNV PAGPGGCQQV DLASVLTPEI
VPPILANADV QECLLPYLPS GESLPQTNTL TSSQFQQALG MFGGALASGQ LGPLMCQFGL
PAEAVEAANK GDVEAFAKAM QNNAKSEAKE GDLKDKKDEE DISRLNYLLS FPELESYI
//
