ID A0A8C6X1K0_NAJNA Unreviewed; 563 AA.
AC A0A8C6X1K0;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 17.
DE SubName: Full=ADRM1 26S proteasome ubiquitin receptor {ECO:0000313|Ensembl:ENSNNAP00000002076.1};
GN Name=ADRM1 {ECO:0000313|Ensembl:ENSNNAP00000002076.1};
OS Naja naja (Indian cobra).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Naja.
OX NCBI_TaxID=35670 {ECO:0000313|Ensembl:ENSNNAP00000002076.1, ECO:0000313|Proteomes:UP000694559};
RN [1] {ECO:0000313|Ensembl:ENSNNAP00000002076.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSNNAP00000002076.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
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DR AlphaFoldDB; A0A8C6X1K0; -.
DR Ensembl; ENSNNAT00000002180.1; ENSNNAP00000002076.1; ENSNNAG00000001451.1.
DR GeneTree; ENSGT00390000013839; -.
DR OrthoDB; 340431at2759; -.
DR Proteomes; UP000694559; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 3.30.70.1820; L1 transposable element, RRM domain; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000694559}.
FT DOMAIN 17..130
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT REGION 514..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 286..347
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 518..547
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 563 AA; 64268 MW; 4A24E75F71F92D5F CRC64;
MSSGALFPTL VPGSRGSSSK YLVEFRAGKM SLKGSTVTPD KRKGLVYIQQ TDDSLIHFCW
KDRTSGNVED DLIIFPDDCE FKRVSQCTTG RVYVLKFKAG SKRLFFWMQE PKTEKDEEHC
RKVNEYLNNP PMPGALGGSG SGGHELSALG GEGGLQSLLG NMSHNQLMQL IGPTGLGGLG
GLGALTGPGL ASLLGSGGPP TSSSSSRPAV PKVPFSRGNL TFWFFPEDVS LLIKEASSAA
SSPSSQRSVE SMLGLEESNS FQNIQAMLQS IQEGLVKIQE TLVKNHEEIR NEMGKLRGEI
RKIGEKTGNF QQMKAKNEQR VQKMEEKEQT EKKVEKVAQV NKGLEEMVIV LEMEKAAYFL
KFQNIKEEKG EDLMDVMTEL LAGALQKTKQ EVQEEIGETF RIHTNYTRRH KLPREVHVRF
TKKTLRDEIL KRSRDKPLKY KRKEMVTLKQ VPRKVRDQRR QYQFLTTQLI KYNVIFRWLI
PEGILVIWQN KRFRLDSLDK AYEFFDHHFV ASEEQESREE IESKRQEEIK AEEKCMQQKE
SENEKRMSRT RRWKSKRTEG DKN
//
