ID A0A8C9CPP9_PHOSS Unreviewed; 703 AA.
AC A0A8C9CPP9;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN Name=ZNF750 {ECO:0000313|Ensembl:ENSPSNP00000028350.1};
OS Phocoena sinus (Vaquita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Phocoenidae; Phocoena.
OX NCBI_TaxID=42100 {ECO:0000313|Ensembl:ENSPSNP00000028350.1, ECO:0000313|Proteomes:UP000694554};
RN [1] {ECO:0000313|Ensembl:ENSPSNP00000028350.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Morin P., Mountcastle J., Fungtammasan C., Rhie A., Rojas-Bracho L.,
RA Smith C.R., Taylor B.L., Gulland F.M.D., Musser W., Houck M., Haase B.,
RA Paez S., Howe K., Torrance J., Formenti G., Phillippy A., Ryder O.,
RA Jarvis E.D., Fedrigo O.;
RT "Phocoena sinus (Vaquita) genome, mPhoSin1, primary haplotype.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPSNP00000028350.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSPSNP00000028350.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_032472747.1; XM_032616856.1.
DR AlphaFoldDB; A0A8C9CPP9; -.
DR Ensembl; ENSPSNT00000031837.1; ENSPSNP00000028350.1; ENSPSNG00000020572.1.
DR GeneID; 116745807; -.
DR KEGG; psiu:116745807; -.
DR CTD; 79755; -.
DR GeneTree; ENSGT00530000063870; -.
DR Proteomes; UP000694554; Chromosome 20.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0061436; P:establishment of skin barrier; IEA:Ensembl.
DR GO; GO:0044091; P:membrane biogenesis; IEA:Ensembl.
DR GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IEA:Ensembl.
DR GO; GO:2000304; P:positive regulation of ceramide biosynthetic process; IEA:Ensembl.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000694554};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 6..57
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 62..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 361..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 577..593
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..616
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..664
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 75397 MW; EB26F78459E5DEF9 CRC64;
MSLLKERKPK KPHYIPRPPG KPFKYKCFQC PFTCNEKSHL FNHMKYGLCK NSITLVSEQD
RIPKCSKPNS SDPKPTNQSD PMAKPTSSKP VPSGLSHLDT KLQHGLAKDD IKENVDLHAC
GPHRCPGQKP TLHKEAAPLS PAPEATAGTQ PVLEGTTRPS AFMPVGEHRL KGQELTEAPE
ALTLTQPPAK AASFHTKSAF HAPGYAWKAG SPFLTPEFPH KIPSTKGFGA TSPYVHPTIA
EYPPHFYTEH GLATIYSPYL LAGNSPECDS PLLSIYGAQD QRHFLPHPGP IPKHLNPAPS
TYDHYRFFQQ YHSNLPIPYG FYRPESAFSS YGLRPPPVAG ISQDQSSHLL EEAALAYPAW
SPSKLNSSNS HKKHTEFEKE SPTPEAKDLS RDGQRDTEGT KMSPRAGSAA TGSPGRPSPT
NFTQTSQPCA GLCSLLDMPA SGAPGSLHPP EQSLTAFKPV KKNTERPHSQ APENRAASPE
SLEAVNADAL AQMGSLEAAP SSPEDDSRAA PLNLSTKPEA EPATTHTTAY GEFVEPQDAP
LNLSVKDPCN ALTSRPSVRS CPRGAEPTAA PTPTPAPQSE TASSGAGPDP SSAEIPVPSP
AGKAHDTRSA DSDEQKQTAA VALCQLAAYS PGNVEPAAQE PACQVDAPTP RAPESQEAHC
DLRPKGQKRT SPRDAGKAQQ GTKKAKPSDT ARVFTLRKRT RVS
//
