ID A0A8D0ARP4_SANLU Unreviewed; 330 AA.
AC A0A8D0ARP4;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 18.
DE SubName: Full=Suppressor of cytokine signaling 9 {ECO:0000313|Ensembl:ENSSLUP00000058955.1};
OS Sander lucioperca (Pike-perch) (Perca lucioperca).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Percoidei; Percidae; Luciopercinae; Sander.
OX NCBI_TaxID=283035 {ECO:0000313|Ensembl:ENSSLUP00000058955.1, ECO:0000313|Proteomes:UP000694568};
RN [1] {ECO:0000313|Ensembl:ENSSLUP00000058955.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSSLUP00000058955.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
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DR AlphaFoldDB; A0A8D0ARP4; -.
DR Ensembl; ENSSLUT00000060641.1; ENSSLUP00000058955.1; ENSSLUG00000025236.1.
DR GeneTree; ENSGT00940000164285; -.
DR Proteomes; UP000694568; Unplaced.
DR GO; GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:TreeGrafter.
DR GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:TreeGrafter.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR022252; SOCS4/SOCS5_dom.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF18; SUPPRESSOR OF CYTOKINE SIGNALING 9 ISOFORM X1; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF12610; SOCS; 1.
DR PRINTS; PR00678; PI3KINASEP85.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000694568};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 237..311
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 26..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 330 AA; 37382 MW; 5572AF4A9952A319 CRC64;
MKLAAERPVS DGFEYGELLS DLETVDQSPL ASEGELEMAG SGSRRLIPRT RRVTARSGQG
TVSSATEMPA PGEGEGRGSS SSRTLRQKIQ DAMGQCFPLK THSAAASAPS PRKIHLTAAT
VVEDVDDRLR ERRRISIEQG VEPPPNAEIH TFEVTAQINP LYKHGPKLAH GMNELAVADR
ASVHQQQQQQ LLLQRQQQAI LPPTEDPKCH DGYRIHTQID YIHCLVPDLL QITNLPCYWG
VMDRYEAETL LEGKPEGTFL LRDSAQEDYL FSVSFRRYGR SLHARIEQWN HNFSFDVHDP
VSSTLRLLRE YHYKQRVRVR RMDTWADYKG
//
