ID   A0A8D0BZB2_SALMN        Unreviewed;       225 AA.
AC   A0A8D0BZB2;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   08-OCT-2025, entry version 18.
DE   RecName: Full=BOS complex subunit TMEM147 {ECO:0000256|ARBA:ARBA00034846};
DE   AltName: Full=Transmembrane protein 147 {ECO:0000256|ARBA:ARBA00034899};
OS   Salvator merianae (Argentine black and white tegu) (Tupinambis merianae).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata;
OC   Teiioidea; Teiidae; Salvator.
OX   NCBI_TaxID=96440 {ECO:0000313|Ensembl:ENSSMRP00000014999.1, ECO:0000313|Proteomes:UP000694421};
RN   [1] {ECO:0000313|Ensembl:ENSSMRP00000014999.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC       Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
CC   -!- SIMILARITY: Belongs to the TMEM147 family.
CC       {ECO:0000256|ARBA:ARBA00034739}.
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DR   Ensembl; ENSSMRT00000017480.1; ENSSMRP00000014999.1; ENSSMRG00000011680.1.
DR   GeneTree; ENSGT00390000013276; -.
DR   OMA; SKCVYAG; -.
DR   Proteomes; UP000694421; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0160064; C:multi-pass translocon complex; IEA:Ensembl.
DR   GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR   GO; GO:0160063; P:multi-pass transmembrane protein insertion into ER membrane; IEA:Ensembl.
DR   GO; GO:0036228; P:protein localization to nuclear inner membrane; IEA:Ensembl.
DR   InterPro; IPR019164; TMEM147.
DR   PANTHER; PTHR12869:SF0; BOS COMPLEX SUBUNIT TMEM147; 1.
DR   PANTHER; PTHR12869; SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF09767; DUF2053; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694421};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        101..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        171..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        200..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   225 AA;  25435 MW;  7C5DC182AFD69EC2 CRC64;
     MTLFHFGNCF ALAYFPYFIT YKCSGLSEYN AFWRCVQAGA TYLFVQLCKM LFLATFFPTW
     EGGAGAYDFI GEFMKATVDL ADLVGLHLVM SRNAGKGEYK IMVAAMGWAT AELIMSRCIP
     LWVGARGIEF DWKYIQMSID SNISLVHYIA TAALVWMFTR YDLPKHYRLP LTFLLGVSVY
     KAFFMESFVH VFLLGSWTAL LVKAVITGLL SLSSLTLFVT LVHSN
//