ID   A0A8E0R308_9EURO        Unreviewed;       171 AA.
AC   A0A8E0R308;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   05-FEB-2025, entry version 8.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 11 {ECO:0000256|RuleBase:RU364147};
DE   AltName: Full=Mediator complex subunit 11 {ECO:0000256|RuleBase:RU364147};
GN   Name=MED11 {ECO:0000256|RuleBase:RU364147};
GN   ORFNames=Aud_010702 {ECO:0000313|EMBL:GIC94204.1};
OS   Aspergillus udagawae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=91492 {ECO:0000313|EMBL:GIC94204.1, ECO:0000313|Proteomes:UP000036893};
RN   [1] {ECO:0000313|Proteomes:UP000036893}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 46973 {ECO:0000313|Proteomes:UP000036893};
RA   Kusuya Y., Takahashi-Nakaguchi A., Takahashi H., Yaguchi T.;
RT   "Draft Genome Sequence of the Pathogenic Filamentous Fungus Aspergillus
RT   udagawae Strain IFM 46973T.";
RL   Genome Announc. 3:e00834-15(2015).
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC       the regulated transcription of nearly all RNA polymerase II-dependent
CC       genes. Mediator functions as a bridge to convey information from gene-
CC       specific regulatory proteins to the basal RNA polymerase II
CC       transcription machinery. Mediator is recruited to promoters by direct
CC       interactions with regulatory proteins and serves as a scaffold for the
CC       assembly of a functional pre-initiation complex with RNA polymerase II
CC       and the general transcription factors. {ECO:0000256|RuleBase:RU364147}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364147}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU364147}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 11 family.
CC       {ECO:0000256|ARBA:ARBA00008186, ECO:0000256|RuleBase:RU364147}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GIC94204.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BBXM02000009; GIC94204.1; -; Genomic_DNA.
DR   Proteomes; UP000036893; Unassembled WGS sequence.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.287.3490; -; 1.
DR   InterPro; IPR019404; Mediator_Med11.
DR   PANTHER; PTHR22890; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11; 1.
DR   Pfam; PF10280; Med11; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364147};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364147};
KW   Transcription {ECO:0000256|RuleBase:RU364147};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364147}.
SQ   SEQUENCE   171 AA;  18327 MW;  D86B660628F22D70 CRC64;
     MAEERSSAQP VQVFTSADRI RQLNEVDKDV AKLIHSAGLA VQALTNARTS DSPDDTSLES
     HKARFKEATS QYFALLSSID VRLRRQVYAL EEAAILAPES ASRTGDLPGA GGGATGVSNP
     LDVSWLNSRK DTVGKDKEAE LWAAARQFVE QLGDSSAASV KVEGGHKMEV D
//