ID   A0A8H3YDI4_9TREE        Unreviewed;       483 AA.
AC   A0A8H3YDI4;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   10-JUN-2026, entry version 13.
DE   RecName: Full=Prephenate/arogenate dehydrogenase domain-containing protein {ECO:0000259|PROSITE:PS51176};
GN   ORFNames=NliqN6_1882 {ECO:0000313|EMBL:GHJ85480.1};
OS   Naganishia liquefaciens.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Filobasidiales; Filobasidiaceae; Naganishia.
OX   NCBI_TaxID=104408 {ECO:0000313|EMBL:GHJ85480.1, ECO:0000313|Proteomes:UP000620104};
RN   [1] {ECO:0000313|EMBL:GHJ85480.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=N6 {ECO:0000313|EMBL:GHJ85480.1};
RA   Han Y.W., Kajitani R., Morimoto H., Parhat M., Tsubouchi H., Bakenova O.,
RA   Ogata M., Argunhan B., Aoki R., Kajiwara S., Itoh T., Iwasaki H.;
RT   "Draft Genome Sequence of a Deep-Sea Yeast, Naganishia (Cryptococcus)
RT   liquefaciens strain N6.";
RL   Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GHJ85480.1}.
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DR   EMBL; BLZA01000011; GHJ85480.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A8H3YDI4; -.
DR   OrthoDB; 5399569at2759; -.
DR   Proteomes; UP000620104; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:TreeGrafter.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:L-tyrosine biosynthetic process; IEA:InterPro.
DR   FunFam; 1.10.3660.10:FF:000004; Prephenate dehydrogenase [NADP(+)]; 1.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 2.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR050812; Preph/Arog_dehydrog.
DR   InterPro; IPR003099; Prephen_DH.
DR   InterPro; IPR012385; Prephenate_DH_fun.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF27505; 6PGD_Tyr1_C; 1.
DR   PIRSF; PIRSF036510; PDH_fung; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000620104}.
FT   DOMAIN          11..297
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   483 AA;  53906 MW;  48696202E092C049 CRC64;
     MSNGIQDISD LQIGLIGMGE ASVEMGKMYA RRLAAGGMKK ICVCDRFERY EALREEMKDV
     PTIQVLKDGH QVSRISDFII YSVEAEFISQ VVSTYGPSTK PNAIVAGQTS VKAPEREAFE
     KYLPDDVHIV SVHSLHGPTV TTEGQPLVII QHRAPDEKVR IVERILESFK SRYVYLTYEE
     HDLVTANTQA VTHAAFLSMG TAWKNSQDYP WETERYVGGI EIVKINIALR IYSNKWHVYA
     GLAILNPSAR EQIRMYAQCA TDIFKLMIEE KKDMLRQRMY EARQGVFGWT PEQEGDAETT
     TGSKQRKPIL LSDRILDQFS LGPKPAAGEP VRPNSHLSLL AMVDCWHKLG IKPYDHLDVA
     GTPVFMLWIG VAEYLFRSTE RLEVAIDCAI GDKTHRSDDT EFVVAARGWS QCVSFGSFDL
     YRNRFEETAS FFAPRFQEAT VIGGKMIKTI LDESAQAKAA AEAKASARVS AAASAAASDK
     TSV
//