ID A0A8H4NID9_9HYPO Unreviewed; 629 AA.
AC A0A8H4NID9;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE SubName: Full=DBF4-regulatory subunit for Cdc7p kinase {ECO:0000313|EMBL:KAF4433467.1};
GN ORFNames=FACUT_8151 {ECO:0000313|EMBL:KAF4433467.1};
OS Fusarium acutatum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=78861 {ECO:0000313|EMBL:KAF4433467.1, ECO:0000313|Proteomes:UP000536711};
RN [1] {ECO:0000313|EMBL:KAF4433467.1, ECO:0000313|Proteomes:UP000536711}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 13308 {ECO:0000313|EMBL:KAF4433467.1,
RC ECO:0000313|Proteomes:UP000536711};
RA Kim H.-S., Busman M., Brown D.W., Divon H., Uhlig S., Proctor R.H.;
RT "Identification and distribution of gene clusters putatively required for
RT synthesis of sphingolipid metabolism inhibitors in phylogenetically diverse
RT species of the filamentous fungus Fusarium.";
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF4433467.1}.
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DR EMBL; JAADJF010000221; KAF4433467.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8H4NID9; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000536711; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000536711};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 567..616
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 164..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..74
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 71174 MW; 0416101319CA83CB CRC64;
MSSRRGPLTN NPNVANSPLR GASALAGYAK QKRSYATVQR EETYGQPPPL KKQVLDNGVQ
RPVRSPTRST RTQVLVQRGA TRPSTKERTS RAAPTNVSRE ADTEKEAWKK HHRAKFPKMV
FYFESIPDDV RARLTKRVNY LGARQEPFFS IDVTHVVTTR TIPPERQEAH QDQNQGHHGE
HNESEEQPQT INPSLLNRNT EARRKLLSEF RNAPSRSQQL DDPLKRTRGS KNNDVLYKAR
EMGKKIWTLE KFQNMLAVLL EAETSHSTYG SRSTATRGNY GASREPNLLQ LLHNERLNGP
SDRDPSAVHR ELCYFKGPHI YVWDMDEKNK PIMVREYPKV ANKADGEWPQ FRSVGNGRCP
FVEDHDVPEK DHRRQREQEK ARLAKREEVA PVLKPPQVPM PKPVTGKRTI AEMEDGQSRA
RAATPTDIFN PARTAMPKAV DARPQNAFTS RAAAGRLFAG EPVASGVQPS NITSAIRSQM
VSSTSGINGA KAGTSKEVHG LQRKVLQKAA PASFDVSSRR LAEVSMDVAS SRSTTMGRHT
SRPAEVQEED AQKTERRTQS QPLKSKRDLK PGYCENCQDK FRDFDEHILS RKHRKFAEND
ENWTELDSLL SQIKRMPKYA SGSDEEEVW
//
