ID   A0A8H5AB90_FUSOX        Unreviewed;       988 AA.
AC   A0A8H5AB90;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   28-JAN-2026, entry version 15.
DE   RecName: Full=Protein argonaute {ECO:0008006|Google:ProtNLM};
GN   ORFNames=FOXYS1_8408 {ECO:0000313|EMBL:KAF5260926.1};
OS   Fusarium oxysporum (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=5507 {ECO:0000313|EMBL:KAF5260926.1, ECO:0000313|Proteomes:UP000558688};
RN   [1] {ECO:0000313|EMBL:KAF5260926.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 39464 {ECO:0000313|EMBL:KAF5260926.1};
RA   Kim H.-S., Busman M., Brown D.W., Divon H., Uhlig S., Proctor R.H.;
RT   "Identification and distribution of gene clusters putatively required for
RT   synthesis of sphingolipid metabolism inhibitors in phylogenetically diverse
RT   species of the filamentous fungus Fusarium.";
RL   Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the argonaute family.
CC       {ECO:0000256|RuleBase:RU361178}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAF5260926.1}.
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DR   EMBL; JAAFOW010001382; KAF5260926.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A8H5AB90; -.
DR   Proteomes; UP000558688; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   CDD; cd02846; PAZ_argonaute_like; 1.
DR   CDD; cd04657; Piwi_ago-like; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 2.170.260.10; paz domain; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR014811; ArgoL1.
DR   InterPro; IPR032472; ArgoL2.
DR   InterPro; IPR032474; Argonaute_N.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR045246; Piwi_ago-like.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR22891; EUKARYOTIC TRANSLATION INITIATION FACTOR 2C; 1.
DR   Pfam; PF08699; ArgoL1; 1.
DR   Pfam; PF16488; ArgoL2; 1.
DR   Pfam; PF16486; ArgoN; 1.
DR   Pfam; PF02170; PAZ; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM01163; DUF1785; 1.
DR   SMART; SM00949; PAZ; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; PAZ domain; 2.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   3: Inferred from homology;
FT   DOMAIN          328..444
FT                   /note="PAZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50821"
FT   DOMAIN          616..920
FT                   /note="Piwi"
FT                   /evidence="ECO:0000259|PROSITE:PS50822"
FT   REGION          1..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..34
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   988 AA;  110665 MW;  34DCA0881990180D CRC64;
     MSDRGRSPSP AGSRGPSGSG RRPSQSPARS ASGSTAGGAA VGYQKPLGFD PAKPQGQDTQ
     GNTRMELPPD AYVAETKKDL FTLRNGRFNT EGKPEQIEVN QYRMTRFDYN KKIYQYDVFI
     SPNPDKIGPV MKKIWAHATT RNALKAYKFD MWLFDGKKLA WSPALVERGE ARFTVDLDEG
     KRPAGGRARE GGKFLVTIRK TTEIRVSALQ GYLEHKISFN NSVQEALNFM DHLVRQWPSK
     NLLAIKRNFY KTGQPGAPLQ DGAIVEVHKG TYASIRMSDN IKQRGVGLGY NIDVANTCFW
     IGNQPMDKMA CNFLATLDGK YGGHTPATIN ELLKPVRDRK TGRWASSDAF KQLRKMRRLK
     FKIKHKGRKN EDKLYTIQDF AFNEKFGEAG ASARTWTFEK DGKDISVYEY YKKEYNVTLR
     LSHLPLIDAG KGGMIPMELA FVEDMQRYPF KLNPEQTAAM IKIAVTRPAI RKRDIQNGAA
     ALQIGQDPFL KEYGVNFEPQ FAKTEARILT APIVRFGQGT AEPRFAGRWD LRGKKFWKQN
     VAPLQNWGFI ALEQQVQLPV MQAFANTFKS TYIGHGGKVT ADPILLPTPG PLRFDAAGAI
     AHAHEQITKQ RGYTQLLFVI VSKKNSGTYE RLKKSADCRF GILTQVVLGN HVQKNNGQYH
     SNVCMKVNAK LGGATSCTPP LWKTPTFFPD NRPTMIVGVD VSHAAPGGVT PSTASMTMSV
     DKDATRYAAV AETNGYRVEM LTPSNIRFMF GELIPRWRAN HQGLVPKHLI YFRDGVGEGQ
     FAYVLDQEVE EIKKYLATIL PGGQMPKFTV IVATKRHHIR FFPQRGDKNG NPLPGTLVER
     EVTHPFMFDF YLNSHVAIQG TARPVHYHVI LDEMNMPVND LQKMIYQQCY SYARSTTPVS
     LHPAVYYAHL ASNRARAHEN VNSSDGFRIG PKGHEIAAEK QAHGASTGLP NRTVEAPPLI
     RLGGALSQTP LDGEQRQRDF FRGTMWYI
//