ID   A0A8H5Z5Q4_9HYPO        Unreviewed;       316 AA.
AC   A0A8H5Z5Q4;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   05-FEB-2025, entry version 8.
DE   SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:KAF5725183.1};
GN   ORFNames=FMUND_78 {ECO:0000313|EMBL:KAF5725183.1};
OS   Fusarium mundagurra.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium fujikuroi species complex.
OX   NCBI_TaxID=1567541 {ECO:0000313|EMBL:KAF5725183.1, ECO:0000313|Proteomes:UP000544331};
RN   [1] {ECO:0000313|EMBL:KAF5725183.1, ECO:0000313|Proteomes:UP000544331}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 66235 {ECO:0000313|EMBL:KAF5725183.1,
RC   ECO:0000313|Proteomes:UP000544331};
RA   Kim H.-S., Busman M., Brown D.W., Divon H., Uhlig S., Proctor R.H.;
RT   "Identification and distribution of gene clusters putatively required for
RT   synthesis of sphingolipid metabolism inhibitors in phylogenetically diverse
RT   species of the filamentous fungus Fusarium.";
RL   Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAF5725183.1}.
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DR   EMBL; JAAOAN010000010; KAF5725183.1; -; Genomic_DNA.
DR   OrthoDB; 3609at2759; -.
DR   Proteomes; UP000544331; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR   Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR013752; KPA_reductase.
DR   InterPro; IPR051402; KPR-Related.
DR   InterPro; IPR013332; KPR_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR21708:SF30; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR   PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR   Pfam; PF02558; ApbA; 1.
DR   Pfam; PF08546; ApbA_C; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000544331}.
FT   DOMAIN          6..164
FT                   /note="Ketopantoate reductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02558"
FT   DOMAIN          197..261
FT                   /note="Ketopantoate reductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08546"
SQ   SEQUENCE   316 AA;  34353 MW;  6853661F8AF5B43E CRC64;
     MDKARILLVG CGGIGCIAAL NLETGGRAEV TAVLRSSYQI VKERGFTINS VDHGQILGFR
     PTEILPSIPD VSKSGISPFD YIICATKNIP VISTPVADLI RPAVTLGYTT ILLLQNGLNI
     QVPVQEAFPS NVILSGISMC GSSEPKSGTI EHNLHDELRI GPFEDFGNAA ERAKDLVARF
     NAGGRCTCQY DDNVTFSRWR KLLYNAVYNP VGALTRLDTG DMQLCPGLVD EVIRPGMKEI
     QAAAAAYGQE LTDEMIEATI MTEPIDAHVS PKNLLGEPLR AAQARQVPTP ILQNHYSLAS
     SYQWKLHSQK DTSEMK
//