ID A0A8H6HIW6_9AGAR Unreviewed; 1039 AA.
AC A0A8H6HIW6;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 11.
DE RecName: Full=R3H domain-containing protein {ECO:0000259|PROSITE:PS51061};
GN ORFNames=DFP72DRAFT_1016602 {ECO:0000313|EMBL:KAF6747190.1};
OS Ephemerocybe angulata.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Ephemerocybe.
OX NCBI_TaxID=980116 {ECO:0000313|EMBL:KAF6747190.1, ECO:0000313|Proteomes:UP000521943};
RN [1] {ECO:0000313|EMBL:KAF6747190.1, ECO:0000313|Proteomes:UP000521943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 144469 {ECO:0000313|EMBL:KAF6747190.1,
RC ECO:0000313|Proteomes:UP000521943};
RG DOE Joint Genome Institute;
RA Steindorff A.S., Carver A., Calhoun S., Stillman K., Liu H., Lipzen A.,
RA Pangilinan J., Labutti K., Bruns T.D., Grigoriev I.V.;
RT "Comparative genomics of pyrophilous fungi reveals a link between fire
RT events and developmental genes.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NFX1 family.
CC {ECO:0000256|ARBA:ARBA00007269}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF6747190.1}.
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DR EMBL; JACGCI010000084; KAF6747190.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8H6HIW6; -.
DR OrthoDB; 6512771at2759; -.
DR Proteomes; UP000521943; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:TreeGrafter.
DR CDD; cd06008; NF-X1-zinc-finger; 5.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR034078; NFX1_fam.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR000967; Znf_NFX1.
DR PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR PANTHER; PTHR12360:SF12; TRANSCRIPTIONAL REPRESSOR NF-X1; 1.
DR Pfam; PF01424; R3H; 1.
DR Pfam; PF01422; zf-NF-X1; 7.
DR SMART; SM00393; R3H; 1.
DR SMART; SM00438; ZnF_NFX; 7.
DR SUPFAM; SSF82708; R3H domain; 1.
DR PROSITE; PS51061; R3H; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000521943};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 847..909
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT REGION 1..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 939..1012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1020..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..22
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..967
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..1002
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1039 AA; 112246 MW; C2B0F5F397516784 CRC64;
MSAIPQSSVA VEGSSSSNPN RRQAPRRRRP RQTGENAPTS GPDVQGAASN SVERPGPPRA
PRQPRRTPQG NQSNQGDRPP KPRAPRPQKP KDDLGPTPGA SRRSRFRGRL TNVPDAAPTS
EPSTLVPDAA PTSTLKPSEK YRTLPQGDDL TSSLIRQLST PPYPDCPICF ASIHPAQPIW
SCSPSTPVVP SAEGQVHYCW TSFHTKCITA WAAKSVKEMS EAWRARGDLE KVGDWRCPGC
QAKREVVPSG YWCFCNTVPE PKLTRLSTPH SCGKPCSRVR DSGCGHPCPL LCHPGPCPPC
QVVTQLDCYC PRHISLSFRC GVDIIGNGKR NLSCGNVCGR VLGCGNHNCT SVCHEGDCAK
CLETEVVKCY CGKEEKQVAC GDGTPKDCFV EGEEPWIGRY TCDNTCERPF DCGIHQCEKA
CHPPTSKPAI CPRSPRVVTH CPCGKGTIAP PGSDSSQYTF PARPNCEAPI PTCASVCSKP
HPQCSHPCES KCHLGPCPPC TVTITRPCRC GATTRRIPCY EVYEKAENGD IQEQEILCDR
PCTSLRACGR HQCRRICCPL ASLATAQRKG KKRAMQQNEV GIGEERGGLH ECDLVCAKML
SCGNHRCEER DHKGPCPPCL RSSFEEMFCP CGRTVLEPPV PCGTRIQCNY PCPRPSPPCG
HPTTPHACHD DSLPCPPCPH LTTKQCACGK KEISNVKCSL EKDKVSCGTV CGKLMSCGFH
HCESLCHGGD CGTCTAPCGK ARKLCFPNHH PCTRPCHAPS ACPETEPCEA IITITCPCGR
IKQAVQCGRR VSHPSGHQVT APKCINECSI AKRNARLAEA LGIDPASKDK DKVVYNDELV
AFARANPRFL SVVEKAFSDF ISSDKRHQVL PHMPPEKRKI AHDLANIYRM DTQLIDQEPQ
RSVQLIRRID TRIPSPVLSA YIASLTPNFG RLADLRSLKS GSSSPVPRSG APTPTASSSS
ATTRGWGSVA GPSRPIGHAV VGSVPPSISS SSSSTLRPAG SGASMPRNRS HTEIKVAVAK
AQVEQEEGGP VVDNWEDDL
//
