ID A0A8H7ME01_9PLEO Unreviewed; 1619 AA.
AC A0A8H7ME01;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 02-APR-2025, entry version 10.
DE RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
GN ORFNames=EKO04_010818 {ECO:0000313|EMBL:KAF9691388.1};
OS Ascochyta lentis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Didymellaceae; Ascochyta.
OX NCBI_TaxID=205686 {ECO:0000313|EMBL:KAF9691388.1, ECO:0000313|Proteomes:UP000651452};
RN [1] {ECO:0000313|EMBL:KAF9691388.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Al4 {ECO:0000313|EMBL:KAF9691388.1};
RA Syme R.A., Farfan-Caceres L., Lichtenzveig J.;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF9691388.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Al4 {ECO:0000313|EMBL:KAF9691388.1};
RA Lee R.C., Farfan-Caceres L.M., Debler J.W., Williams A.H., Henares B.M.;
RT "Reference genome assembly for Australian Ascochyta lentis isolate Al4.";
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF9691388.1}.
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DR EMBL; RZGK01000021; KAF9691388.1; -; Genomic_DNA.
DR OrthoDB; 129353at2759; -.
DR Proteomes; UP000651452; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042393; F:histone binding; IEA:TreeGrafter.
DR GO; GO:0000077; P:DNA damage checkpoint signaling; IEA:TreeGrafter.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:TreeGrafter.
DR CDD; cd17745; BRCT_p53bp1_rpt1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR047249; BRCT_p53bp1-like_rpt1.
DR InterPro; IPR041297; Crb2_Tudor.
DR InterPro; IPR047252; TP53BP1-like.
DR PANTHER; PTHR15321:SF3; TP53-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR15321; TUMOR SUPPRESSOR P53-BINDING PROTEIN 1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF18115; Tudor_3; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000651452}.
FT DOMAIN 1317..1445
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 188..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 633..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 925..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1564..1583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..220
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..431
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..668
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 704..718
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..793
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1042..1051
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1057..1078
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1079..1091
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1269..1290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1307..1319
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1619 AA; 175827 MW; A80F3DDABC4504E7 CRC64;
MTDSQAFTLL EEGFYDVCDL SRAAPRVRSP ASTPSRFADR WSHASALFTS LTRRLQDPSQ
LSQALRQRAG SEPGLYLTTS TESHPSLVSA PASTFTVPPH PLLGAPQLLP VAAPAVRPPA
PCTRRASTAN HVKPGVSKHN SAPVSTAPMT DAAIAPNMSH SLAAMDAPGD TQPDSQMHRE
WTSGIFGTAE TTTRMPSPRS GPKSLFTEHD DDDDDDDAEP LTDGLQLVES SQLQQDAAMT
SPTALEDDRG PYLRTEQAFT SPLKFETPAV AGRKRDHLGH MLSSTGGFET TPDTIASASA
SAFGGALGKS GIGQPLSLTQ AFDLTQARTS PLLAGTEDPI FQRPSPNFNN VRHSSPIPAL
SSPIKVLRNE RSDPVVRSSS EPRSEYVTMK ESQERRKHTK GPQRATLVQE DSWEEPTAAQ
KRMQRQKRKE QSHREAGLSL SSISAPASTK SHVARKRKEN ACYSLTAQHT IPRHVWHDGV
HEDKDVAMDD PSQHLAPEGD EAEHSPDDLS QDVAVAAQAP MRYHGLENGV QVPKTSSHPQ
RTQPEHVPAN GSHRPSPSSQ VQRESQIQAP TSQSLLRAVP HSSRGSVAVM DSQPDVIAHP
KRLSRPPDLM RFPSSPSINQ YSINQTTLAS KTGYTSQMVS SSMIQMPPQL SPEDEEDVEE
EETPEEEERV PSSPPMLTDE LTYDEHTYNE HPDGNEDHGV EEAAAGEEDV LMEDEEELPV
AQRELVDNEA LAVEAGQGDV DENVEPDLLQ PIKVDAGTDQ EIPETLEEDH QHEMNRQDTT
KHPKGLRTEK EQASTKPAPS LQRQNTIPDT DALDETQPSY FLDETLAVQG EASPNQVAQH
RMAVQEDTSN TEPSETAREQ REMSQSYMPA PASSRDEGSD PVHSVNRIRS LNDIANLPAT
QLSAAEEEIE IPCLSGFDDA DGDAHMASSV PATPATKRRK TATIAKSSVF RSPAKSAGVT
EEQVPPSPLK RIQQMREDTP PTASAQEREE QGALAAAQAR QDVQMVAYGR PAVLKSRDSS
RPAKPQNSKK GSLKSARAII ATMSSPINSP SKPKASTIVQ RTTPATPSRK VTASTSKSID
VEMRDTDHSP DELASSPPPS TTQLPVRLTP RKVEVHAEGV VVPNRVFASW PGSHFYPATC
LGRSDSKHLQ VRFDDGNTTS LDSFQVRSLD LRPGDQVKVD EPGMKKHTYV IVHLGDKCSD
LENYEFPMTD RYGHVTATLE EKQRDSLPAA KAPHPAKQAS VPIASIYLTT QLWGRLRDRS
FQLPALCSPS KSASRLGTPI TTEALTTPSF TRRGHAAPSL LKDATNRAGS VASSSRSGSG
TFSNMAFVLT STGDSMDKDA VARAIRNNGG RVLEQGFHEL FDTESIELSA SQSRRTSVSS
TDGVGVLALK EEYRKLGFVA LVTDSHSRST KYLQALALNV PCLHLRWVND SLSASHALSF
ARYLLPAGVS KYLDPNGIVR SRAMRIYDPS SDDVSFEKTF EARDLLLQGR SILLVTGKSK
KEIEKRQPFV FLSHALGSAN VGRCTDLAVA AQLLTQGHWG WVYVDGDQSS LADAAAELFG
TGAPAKSAKG SLKKSKKRKR DDGDADELLA KGEIAGRKIR IASAEFVIQS LILGALVDE
//
