ID A0A8H7RQ63_9FUNG Unreviewed; 1369 AA.
AC A0A8H7RQ63;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 05-FEB-2025, entry version 7.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=INT47_001095 {ECO:0000313|EMBL:KAG2213826.1};
OS Mucor saturninus.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=64648 {ECO:0000313|EMBL:KAG2213826.1, ECO:0000313|Proteomes:UP000603453};
RN [1] {ECO:0000313|EMBL:KAG2213826.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WA0000017839 {ECO:0000313|EMBL:KAG2213826.1};
RA Muszewska A., Okrasinska A., Steczkiewicz K., Drgas O., Orlowska M.,
RA Perlinska-Lenart U., Aleksandrzak-Piekarczyk T., Szatraj K.,
RA Zielenkiewicz U., Pilsyk S., Malc E., Mieczkowski P., Kruszewska J.S.,
RA Biernat P., Pawlowska J.;
RT "Metabolic potential, ecology and presence of endohyphal bacteria is
RT reflected in genomic diversity of Mucoromycotina.";
RL Submitted (DEC-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG2213826.1}.
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DR EMBL; JAEPRD010000002; KAG2213826.1; -; Genomic_DNA.
DR OrthoDB; 436262at2759; -.
DR Proteomes; UP000603453; Unassembled WGS sequence.
DR GO; GO:0000779; C:condensed chromosome, centromeric region; IEA:TreeGrafter.
DR GO; GO:0000796; C:condensin complex; IEA:TreeGrafter.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042393; F:histone binding; IEA:TreeGrafter.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0010032; P:meiotic chromosome condensation; IEA:TreeGrafter.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000603453}.
FT DOMAIN 76..229
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1025..1189
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 466..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1250..1369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..496
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1250..1267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1268..1282
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1304..1336
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1345..1354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1355..1369
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1369 AA; 157682 MW; 281847E8C1CAA4AF CRC64;
MRDFVLTDEL LKIQGNVSNY YIPNEIDIAG KSDHDLARFL NEIADNIQVS SENIADPVVF
DKIRSFLKYF TSVQPRILSR LFDIILSAFR VEIKSTKDDL DQNEKDTFNN HRNYLELYSY
SVHWFLLLVE DNTTTSKMVV RRAKNSTNDL KTFDWSTQKL KAFDLASWLL DLKLSKIWTL
TPDRVHFVTL FTKPAYQLFE NPAHAKSSQI KERIFRILSL CIKNYDHLHV AQTTIMQNLQ
YWEHSAEPMA ELLIYMVEKE NYNQLADEIL REISNREFKD TTTKEVKDSP NPKTFATFLQ
KLADLSPKTI LKNLGVLINQ LDSDSYMMRT AIVDILGNMI IELSRTSQDN PNQVDQINDF
FDILEHRMLD PTAYVRQKVL QVYLRLFELK AKFPKRRQAA TELAIRHLQD KSSIVRKYAI
RVLTTLISTH PYIMYGGELN LEEWNSRLLT LRTEIENVAL EKDPETFVLT EKPVTEDEEV
PVTGDEEKPE QDEDTEMKDA SAIENETTEE ADKENQPGTQ SDNPLENPTE RPITTTTTTT
TTRVSPEKLQ QLVLMRTFHV DAVKFIEQIH IAIPIITQLL SSKSKAEVLE SMDFLVIGYN
YKVKLSTDGI KKMLHLIWTK DTSDEGKGIK MKLLSCYENL YLSIDSKRSK KDNVSRIAKN
LIELTYNTNL AELTSLEQVL STLMKENKVA YDVIEKLWSV YGFTKGRIQK SQRRGAIIIL
GMLAKAKTKI VSEKIDLMLK IGLGPLGKAD QSLSRYTCMA LQRLEGIKTK EKGRGVQEGI
RFPIQHPIFS RLKDVIENTT ASTEWFSLAE QAINTIYKLC ENPEILCETI IRDKTIKVFG
MKEIVEATNN DLDSPNDVMA LDYDLSMTQQ ALPFPQHAIH QSSSELSQLL FLVGHIALKQ
IVHLEIIESA WKRKKAQKET VEGGNNEKTE VDDELEQVGG TAEDDIGEAL IRIREREILF
GPNSLLGRFG PLLSEVCARN KVYTDRTLQI TATLALAKFM CVSSDFCEKN LQLLFTILEK
SKDATIRSNI VIALGDMAVC FNTLIDDNIT FLYNRLSDSD TIVKKNTVMV LTHLILNGMV
KVKGQISEMA KCLEDSDQRI VDLAKLFFTE LASKDNAIYN NLPDIISNLT STQPERLEEE
SFKRIMKFIF SFDFTEKEKQ AENIVDKLCQ RFLTAQDERN WRDIAYCLSL LPFKTEKTFK
KLLEGWPSYQ DKIHEDAVHK SFLEIISKGR FQKTQKPELK ALIDELEQKV EKQRGGPEVV
EKPDKTTKKA TRVVKTERRK SKQSTTTTVL PTRELRKRKR VIQEDELEEE ESNMGSEVEM
EQAADDDDEE EEEEEVLTPR RRNRSSQEQK KSKEEEEEDE EDEEEEDDD
//
