ID A0A8H7SQM8_9FUNG Unreviewed; 365 AA.
AC A0A8H7SQM8;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 02-APR-2025, entry version 14.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=INT48_005417 {ECO:0000313|EMBL:KAG2232527.1};
OS Thamnidium elegans.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Thamnidium.
OX NCBI_TaxID=101142 {ECO:0000313|EMBL:KAG2232527.1, ECO:0000313|Proteomes:UP000613177};
RN [1] {ECO:0000313|EMBL:KAG2232527.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WA0000018081 {ECO:0000313|EMBL:KAG2232527.1};
RA Muszewska A., Okrasinska A., Steczkiewicz K., Drgas O., Orlowska M.,
RA Perlinska-Lenart U., Aleksandrzak-Piekarczyk T., Szatraj K.,
RA Zielenkiewicz U., Pilsyk S., Malc E., Mieczkowski P., Kruszewska J.S.,
RA Biernat P., Pawlowska J.;
RT "Metabolic potential, ecology and presence of endohyphal bacteria is
RT reflected in genomic diversity of Mucoromycotina.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG2232527.1}.
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DR EMBL; JAEPRE010000108; KAG2232527.1; -; Genomic_DNA.
DR OrthoDB; 10264956at2759; -.
DR Proteomes; UP000613177; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000613177};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 23..331
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 27..76
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 365 AA; 42692 MW; 947F73B80DC391E9 CRC64;
MLFETEGSSA ASSYADHDEI ENFIDRCSIC FYEQLDLCLE GCRDQFCHGC FQRYIVDVVK
SSWGLSVTPI SCPVCTELIP KHEWSQYVPQ SITDTYDKFN KPYRSYIRTC HHCETDLIPC
VYPNNKPNNS KLFCDLMESM LQTCEEGENH KNHTEHISVK RWLSVNKRQD WSDTKLPTHY
KHIMNNVNTF ERNHAKFPRF AYQISIEYLN LCENPEIWKQ LQFAHIRLFR DMKCFNCKAS
ICLHCGYDSH FNTGCEENMH NISKTLKDKD TRTTIKWKIQ HSRQCPNCSI MINRDEGCNK
VDCSYCGFCF CWACRSSWSD GCGFYRCSNS TNDLCYTESS EEKTELGVPN IKNIQARLIT
PMDLD
//
