ID A0A8H7UDC6_MORIS Unreviewed; 540 AA.
AC A0A8H7UDC6;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 28-JAN-2026, entry version 16.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=INT43_001651 {ECO:0000313|EMBL:KAG2178805.1};
OS Mortierella isabellina (Filamentous fungus) (Umbelopsis isabellina).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Umbelopsidomycetes; Umbelopsidales; Umbelopsidaceae; Umbelopsis.
OX NCBI_TaxID=91625 {ECO:0000313|EMBL:KAG2178805.1, ECO:0000313|Proteomes:UP000654370};
RN [1] {ECO:0000313|EMBL:KAG2178805.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WA0000067209 {ECO:0000313|EMBL:KAG2178805.1};
RA Muszewska A., Okrasinska A., Steczkiewicz K., Drgas O., Orlowska M.,
RA Perlinska-Lenart U., Aleksandrzak-Piekarczyk T., Szatraj K.,
RA Zielenkiewicz U., Pilsyk S., Malc E., Mieczkowski P., Kruszewska J.S.,
RA Biernat P., Pawlowska J.;
RT "Metabolic potential, ecology and presence of endohyphal bacteria is
RT reflected in genomic diversity of Mucoromycotina.";
RL Submitted (DEC-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG2178805.1}.
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DR EMBL; JAEPQZ010000007; KAG2178805.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A8H7UDC6; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000654370; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000654370};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 82..130
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 441..488
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 253..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..301
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..443
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..519
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 540 AA; 61298 MW; 1CC16EE061F45C97 CRC64;
MESSAKTSNT VFQSRCNRTP LSQLNKVDSV WRESRTYARS AIQALELKKQ QQQQENMQRH
SRNTAGAATK PVLLADERWA RAYIKAFPSF KFYFDGIEDL TRRRLEEKVK ILGATVEQFF
SAKCTHIVTG RPVPEESKPL AQKKPENASR DGDIFEIAHK HKIKIWSVDK LQNRILPILF
DNLKHHELPN DHLQHRPKPQ ELPRMLQQEK VFGPSTSKRG EHHGPNFVRF NGHFIFVEDV
TGSYRPIVVK EYPPCDDPNK HTPAWPTLRK NKGNKSPFVR EGHSDNRQDD GQVAKKEEKP
VEVTQQLRPK TELPAARPNL KPAMSLRALN NEQVEKLEVH NSGFAESKAS LGTPSLNASG
MHQFGTSRVV STSGSAVHGL PQPLPPGENI NRLDRRTITN IKANDSPLAV HNKAKADAQV
NAQAAIPQAS KRQKGVLGKK RPPPKNFCEN CRQRFYDLKE AKPRHREYAS NAENFADLDK
IIELTRRRYK PNLPSVKAVS RSEVIDGPLP EDEIPDTQEP EPSSTFVVDD SWEKFADIVW
//
