ID A0A8H7XS01_PSICU Unreviewed; 377 AA.
AC A0A8H7XS01;
DT 19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2022, sequence version 1.
DT 05-FEB-2025, entry version 10.
DE RecName: Full=6-phosphogluconate dehydrogenase C-terminal domain-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=JR316_009328 {ECO:0000313|EMBL:KAG5165743.1};
OS Psilocybe cubensis (Psychedelic mushroom) (Stropharia cubensis).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Psilocybe.
OX NCBI_TaxID=181762 {ECO:0000313|EMBL:KAG5165743.1, ECO:0000313|Proteomes:UP000664032};
RN [1] {ECO:0000313|EMBL:KAG5165743.1, ECO:0000313|Proteomes:UP000664032}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGC-MH-2018 {ECO:0000313|EMBL:KAG5165743.1,
RC ECO:0000313|Proteomes:UP000664032};
RA Mckernan K.J., Crawford S., Trippe A., Kane L.T., Mclaughlin S.;
RT "Psilocybe cubensis genome.";
RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG5165743.1}.
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DR EMBL; JAFIQS010000009; KAG5165743.1; -; Genomic_DNA.
DR OrthoDB; 3609at2759; -.
DR Proteomes; UP000664032; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR051402; KPR-Related.
DR InterPro; IPR013332; KPR_N.
DR PANTHER; PTHR21708:SF43; KETOPANTOATE REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000664032};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..173
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 264..363
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 377 AA; 41781 MW; 9F314E33BA9576E5 CRC64;
MSESLKEVLV VGFGAVGAIY SLILKRSGLA RVTCVARSNF NAINDSGVQF RSRKYGSIDG
WRPHRLCKSV HDAADQQYSY VVVTTKAVPD LVKTSQILAP LFSKEYIEKF SQPTYVLLQN
GVNVEVDLYD ALKEAIPSGK PQIISCALWI YTNLVGLDIV EHSDFDRVAI GVYRHKNNSV
IANSPEESNL LKDFGNLLET GGSTLITVPE IQRMKFTKNF WNITFNSIAT LTNYPLPALF
RPAPGEGSVA YEPYVSPTTA DHISTYTMPV IRKMLEELIA IGRALGYPDS KDGLPSSIVD
NALDGTREIH EKADCTHVPS MLLDAQKGQP IEVEVIVGEV IRMAKSHKVE TPRLETLYAL
LLVVQNQTLR KLESRKP
//
