ID A0A8I3X389_CALJA Unreviewed; 564 AA.
AC A0A8I3X389;
DT 25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 1.
DT 10-JUN-2026, entry version 21.
DE SubName: Full=Synapsin II {ECO:0000313|Ensembl:ENSCJAP00000092181.1};
GN Name=SYN2 {ECO:0000313|Ensembl:ENSCJAP00000092181.1};
OS Callithrix jacchus (White-tufted-ear marmoset) (Simia Jacchus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000092181.1, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000092181.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000092181.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2026) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Synapse {ECO:0000256|ARBA:ARBA00034103}.
CC -!- SIMILARITY: Belongs to the synapsin family.
CC {ECO:0000256|ARBA:ARBA00008243}.
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DR AlphaFoldDB; A0A8I3X389; -.
DR Ensembl; ENSCJAT00000133979.1; ENSCJAP00000092181.1; ENSCJAG00000016647.5.
DR GeneTree; ENSGT00940000156062; -.
DR Proteomes; UP000008225; Chromosome 15.
DR GO; GO:0030672; C:synaptic vesicle membrane; IEA:TreeGrafter.
DR GO; GO:0007269; P:neurotransmitter secretion; IEA:InterPro.
DR FunFam; 3.40.50.20:FF:000008; Synapsin III; 1.
DR FunFam; 3.30.470.20:FF:000151; Synapsin-2; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR001359; Synapsin.
DR InterPro; IPR020898; Synapsin_ATP-bd_dom.
DR InterPro; IPR019736; Synapsin_P_site.
DR InterPro; IPR020897; Synapsin_pre-ATP-grasp_dom.
DR PANTHER; PTHR10841; SYNAPSIN; 1.
DR PANTHER; PTHR10841:SF20; SYNAPSIN-2; 1.
DR Pfam; PF02078; Synapsin; 1.
DR Pfam; PF02750; Synapsin_C; 1.
DR Pfam; PF10581; Synapsin_N; 1.
DR PRINTS; PR01368; SYNAPSIN.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR PROSITE; PS00415; SYNAPSIN_1; 1.
PE 3: Inferred from homology;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 114..215
FT /note="Synapsin pre-ATP-grasp"
FT /evidence="ECO:0000259|Pfam:PF02078"
FT DOMAIN 262..398
FT /note="Synapsin ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF02750"
FT REGION 20..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..40
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..57
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..79
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..456
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..466
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..486
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..516
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 564 AA; 61154 MW; F06E4D2D355679A4 CRC64;
MMNFLRRRLS DSSFIANLPN GYMTDLQRPE PQQPPPPPGP GAASASASAA PLAASPGPER
RPPPASAPAQ QPAPQPAPTP SVGSSFFSSL SQAVKQTAAS AGLVDAPVPA PAARKAKVLL
VVDEPHADWA KCFRGKKVLG DYDIKVEQAE FSELNLVAHA DGTYAVDMQV LRNGTKVVRS
FRPDFVLIRQ HAFGMAENED FRHLIIGMQY AGLPSINSLE SIYNFCDKPW VFAQLVAIYK
TLGGEKFPLI EQTYYPNHKE MVKVENHYDF QDIASVVALT QTYATAEPFI DSKYDIRVQK
IGNNYKAYMR TSISGNWKTN TGSAMLEQIA MSDRYKLWVD TCSEMFGGLD ICAVKAVHGK
DGKDYIFEVM DCSMPLIGEH QVEDRQLITE LVISKMNQLL ARTPALSPQR PLTTQQPQSG
TLKDPDSSKS PPQRPPPQGG PGQPQGMQPP GKVLPPRRLP PGPSLPPSSS SSSSSSSSAP
QRPGGPTTHG DAPSSSSSLA EVQPPLAAPP QKPQPHPQLN KSQSLTNAFS FSESSFFRSS
ANEDEAKAET IRSLRKSFAS LFSD
//
