ID A0A8I6RLZ9_CIMLE Unreviewed; 468 AA.
AC A0A8I6RLZ9;
DT 25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 1.
DT 28-JAN-2026, entry version 17.
DE RecName: Full=Lysophospholipid acyltransferase 7 {ECO:0000256|ARBA:ARBA00093678};
OS Cimex lectularius (Bed bug) (Acanthia lectularia).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Cimicomorpha; Cimicidae; Cimex.
OX NCBI_TaxID=79782 {ECO:0000313|EnsemblMetazoa:XP_014245873.1, ECO:0000313|Proteomes:UP000494040};
RN [1] {ECO:0000313|EnsemblMetazoa:XP_014245873.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2022) to UniProtKB.
CC -!- PATHWAY: Lipid metabolism; phospholipid metabolism.
CC {ECO:0000256|ARBA:ARBA00005074}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the membrane-bound acyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010323}.
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DR RefSeq; XP_014245873.1; XM_014390387.2.
DR AlphaFoldDB; A0A8I6RLZ9; -.
DR EnsemblMetazoa; XM_014390387.2; XP_014245873.1; LOC106664559.
DR GeneID; 106664559; -.
DR KEGG; clec:106664559; -.
DR CTD; 33900; -.
DR OMA; TNMIQML; -.
DR OrthoDB; 7663182at2759; -.
DR Proteomes; UP000494040; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044233; C:mitochondria-associated endoplasmic reticulum membrane contact site; IEA:TreeGrafter.
DR GO; GO:0071617; F:lysophospholipid acyltransferase activity; IEA:TreeGrafter.
DR GO; GO:0030258; P:lipid modification; IEA:TreeGrafter.
DR GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:TreeGrafter.
DR InterPro; IPR049941; LPLAT_7/PORCN-like.
DR InterPro; IPR004299; MBOAT_fam.
DR PANTHER; PTHR13906:SF16; LYSOPHOSPHOLIPID ACYLTRANSFERASE 7; 1.
DR PANTHER; PTHR13906; PORCUPINE; 1.
DR Pfam; PF03062; MBOAT; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000494040};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 468 AA; 54584 MW; 795BD0C51CA393BA CRC64;
MDKDDVIYVI LLLFSIGFGK VIRTIEDVKK KRNLATAVGF LIVLAVSGRH IWHSLCLILV
NAFIITSLEK TVIPAVSFAF SFTYLIFFRM TEYIGMSSPS GHSNMVQMIL TLKLVGLAFE
VKDTHKGITE GRKDPEFEMS KIPNPTIPSI IHYSFCYIGV LTGPYYSYKT YLDMLNLQFS
RFTKCSQYAV QRLKMLPFYG FVFVLANYYF PFEYALAEEF YEDRHFMYRL WYSVPIFLQF
RMRMYIGMRM SEAVCIMAGA GCYPSFSDPK PGKGPSKEYV QLYNIRNNLK KAQACEYDFK
AIHNIEPAGA EFDMTVRNSM KSWNMTVQYW LANYVFKRFP VNSLRLLATF SVSALWHGIY
AGYYCTICSV PFYLPIEDIY SRRLKTIQVS SFVSNVWRIF AVCWRLFLMG YWGITFRLLT
LEASFKYWKS VYFLPTIFTF VLYGLSFLIF KKRTNNGENT RSSREKGD
//
