ID A0A8J1JHZ0_XENTR Unreviewed; 418 AA.
AC A0A8J1JHZ0;
DT 25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE SubName: Full=Transcriptional enhancer factor TEF-1 isoform X5 {ECO:0000313|RefSeq:XP_031756271.1};
GN Name=tead1 {ECO:0000313|RefSeq:XP_031756271.1,
GN ECO:0000313|Xenbase:XB-GENE-5909149};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Proteomes:UP000008143, ECO:0000313|RefSeq:XP_031756271.1};
RN [1] {ECO:0000313|RefSeq:XP_031756271.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_031756271.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_031756271.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR002603}.
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DR RefSeq; XP_031756271.1; XM_031900411.1.
DR AlphaFoldDB; A0A8J1JHZ0; -.
DR GeneID; 100158507; -.
DR AGR; Xenbase:XB-GENE-5909149; -.
DR CTD; 7003; -.
DR Xenbase; XB-GENE-5909149; tead1.
DR Proteomes; UP000008143; Chromosome 4.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0035329; P:hippo signaling; IEA:InterPro.
DR FunFam; 2.70.50.80:FF:000001; Transcriptional enhancer factor TEF-1, putative; 1.
DR Gene3D; 2.70.50.80; -; 1.
DR Gene3D; 6.10.20.40; TEA/ATTS domain; 1.
DR InterPro; IPR000818; TEA/ATTS_dom.
DR InterPro; IPR038096; TEA/ATTS_sf.
DR InterPro; IPR050937; TEC1_TEAD_TF.
DR InterPro; IPR016361; TEF_metazoa.
DR InterPro; IPR041086; YBD.
DR PANTHER; PTHR11834; TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED; 1.
DR PANTHER; PTHR11834:SF4; TRANSCRIPTIONAL ENHANCER FACTOR TEF-1; 1.
DR Pfam; PF01285; TEA; 1.
DR Pfam; PF17725; YBD; 1.
DR PIRSF; PIRSF002603; TEF; 1.
DR PRINTS; PR00065; TEADOMAIN.
DR SMART; SM00426; TEA; 1.
DR PROSITE; PS00554; TEA_1; 1.
DR PROSITE; PS51088; TEA_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR002603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR002603};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR002603};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR002603}.
FT DOMAIN 10..86
FT /note="TEA"
FT /evidence="ECO:0000259|PROSITE:PS51088"
FT DNA_BIND 10..86
FT /note="TEA"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00505"
SQ SEQUENCE 418 AA; 46912 MW; DEE20984946B18AC CRC64;
MSDSADKPMD NDAEGVWSPD IEQSFQEALA IYPPCGRRKI ILSDEGKMYG RNELIARYIK
LRTGKTRTRK QVSSHIQVLA RKKVREIQAA IKVTNMDQTA KDKALQHMAA MSSAQIVSAT
AIHNKLGLPG IPRPAFPAAP GYWPGMIQTG QPGSSQDVKP FAQQAYPIQP SATAPIPGTY
SVSGFEPAPP PASSVPAWQG RSIGTTKLRL VEFSAFLEQQ RDPDAYNKHL FVHIGQANHS
YSDPLLESVD IRQIYDKFPE KKGGLKELFG KGPQNAFFLV KFWADLNCNI QDDTGAFYGV
TSQYESSENM TITCSTKVCS FGKQVVEKVE TEYARFENGR FVYRINRSPM CEYMINFIHK
LKHLPEKYMM NSVLENFTIL LVVTNRDTQE TLLCMACVFE VSNSEHGAQH HIYRLVKE
//
