ID A0A8J3HTU0_9CHLR Unreviewed; 679 AA.
AC A0A8J3HTU0;
DT 25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 1.
DT 28-JAN-2026, entry version 18.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=KSX_20400 {ECO:0000313|EMBL:GHO43877.1};
OS Ktedonospora formicarum.
OC Bacteria; Bacillati; Chloroflexota; Ktedonobacteria; Ktedonobacterales;
OC Ktedonobacteraceae; Ktedonospora.
OX NCBI_TaxID=2778364 {ECO:0000313|EMBL:GHO43877.1, ECO:0000313|Proteomes:UP000612362};
RN [1] {ECO:0000313|EMBL:GHO43877.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SOSP1-1 {ECO:0000313|EMBL:GHO43877.1};
RA Yabe S., Wang C.M., Zheng Y., Sakai Y., Cavaletti L., Monciardini P.,
RA Donadio S.;
RT "Taxonomic study of unclassified bacteria belonging to the class
RT Ktedonobacteria.";
RL Submitted (OCT-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GHO43877.1}.
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DR EMBL; BNJF01000001; GHO43877.1; -; Genomic_DNA.
DR RefSeq; WP_220193322.1; NZ_BNJF01000001.1.
DR AlphaFoldDB; A0A8J3HTU0; -.
DR Proteomes; UP000612362; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:InterPro.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR FunFam; 3.40.50.300:FF:001064; Selenocysteine-specific translation elongation factor; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000612362}.
FT DOMAIN 1..170
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 679 AA; 74932 MW; 9DB6C51661EED7A6 CRC64;
MSCIGTAGHV DHGKSALVQA LTGIDPDRLA EEKARGMTID LGFAWLTLPH GREVSIIDVP
GHEDFIKNML AGVGGIDAAL LVVAADEGIM PQTREHLAIL DLLRVSQGVV ALTKADLVDD
EWLELVREEI AELIRPTTLA QASILPVSAY TGKGLPQLLA ELERLLDSSE ERQDIARPRL
PIDRVFTLTG FGTVVTGTLL DGSFRLGQEI EILPGRQRTR IRGLQMHKQS IESTGPGHRV
AINLPNISRS DLKRGDVVTL PGQLRSTVLL DARISLLADA ERSLTHNTQV EFYCGSQEIP
ARVRLLDTEE LMPGESAWVQ LRFSRPAVAA RRDAFVLRIP SPSFTIGGGE VIDVRPRYHR
RFQRPILEAL ERLRHGLPEE LVLVALDRRT HASNSGNTGG TSPKVRPTIE GYDLAEVARL
ANLAEDVTGQ VLKSLLLEGR VRHIRAKGAP VSGTDDIGEE KAGLWFARSA WDAFVEESVR
LVASYHRQYP LREGFSKEEW RSRLHLTPRQ ATELFAVLVD DGVMEAVALS EEALLIEATR
RSTGLIRLPG FQPTFTPEQR RQVDALEQAF RRQPYGPPVR AEAEKIAEPE VIAALIGQGT
LVKLGEDVLF LRTTYDEAVS RLTAYLRAHG TMTAAEARDA LGTSRKYVLP LLEHLDLMRV
TKRVGDVRQL ASEPKQSIS
//
